Protein Alignment eIF3d2 and eif3d

DIOPT Version :9

• Sequence 1: NP_731675.1
• Gene: eIF3d2 / 41475
• FlyBaseID: FBgn0037994
• Length: 551
• Species: Drosophila melanogaster
• Sequence 2: NP_989075.1
• Gene: eif3d / 394672
• XenbaseID: XB-GENE-942853
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 555
• Identity: 296/555 - (53%)
• Similarity: 389/555 - (70%)
• Gaps: 31/555 - (5%)

  Fly     5 APFIKPYVEYNEHGWGPCEVPE--LDVPYQPFCKSDRLGKICDWT-AMVPEKKFPSKYASTFGNN 66
            |.|..|.:..|..|||||.||:  .|:|||||.|.|||||:.||| |...:|::.:||:|.||..
 Frog     2 AKFQAPVINDNPLGWGPCAVPDQFKDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGG 66

  Fly    67 SQYAYFYEDDDSTFHLVDTTGSKATKPYQRGRYRPNMRNNVRSRGRTGRGTPNIASLGGSTAGGA 131
            ||||||:::|:::|.|||||..:.| .|||.|.|...||..|.:.|......|:.:|
 Frog    67 SQYAYFHDEDETSFQLVDTTKMQKT-AYQRNRLRFAQRNLRRDKDRRNMLQFNMQTL-------- 122

  Fly   132 TASTTKYGKGRNTRNTQNMGRRFG--------RNAPTRIRESSVMVQSDWVSIEEIDFPRLLKLA 188
             ..:.|..:....|..:...::||        ..|..:.|:|||.|:|||...||:|||||:|:.
 Frog   123 -PKSAKQKERDRLRLQKKFQKQFGVRQKWDQKSQAQLKPRDSSVEVRSDWEVKEEMDFPRLMKMR 186

  Fly   189 LPNIKDGKDIATCGWLEFYDKLYDRVNLRNEKPLQKMDRVVHTVTTTDDPVIRRLSRTMGNVFAT 253
            ...:.|..||..||.||||||.:||:..|||:||:.:.|:.||||||||||||:|::|.||||||
 Frog   187 YMEVSDPLDIECCGALEFYDKAFDRITTRNERPLKSIKRIFHTVTTTDDPVIRKLAKTQGNVFAT 251

  Fly   254 DEILSTIMCCTRSNYSWDVVVEKLGTKVFLDKRYNDQFDLLTVNETSVEPPMDEEGSINSAHSLA 318
            |.||:|:||||||..|||:||:::|:|:|.|||.|..||||||:||:.|||.|:..|:||..:||
 Frog   252 DAILATLMCCTRSVNSWDIVVQRVGSKIFFDKRDNSDFDLLTVSETANEPPQDDVNSLNSPRNLA 316

  Fly   319 MEATLINHNFSQQVLRIGDQEPRFMFEEPNPFEEPGVD---LASIGYRYRQWDLGNDVVLIARCK 380
            ||||.||||||||.||:|.:  :..|..||||.|..||   :||:.||||:|.||:|:.|:.||:
 Frog   317 MEATYINHNFSQQCLRMGKE--KHTFPNPNPFIEDDVDKNEVASVAYRYRRWKLGDDIDLVVRCE 379

  Fly   381 HNGVIQGPNGDVQFLSIKALNEWDSKVTNSVEWRQKLDTQRGAVLASELRNNACKLARWTVEAVL 445
            |:|.:.|.||:|.|::||.||||||:..|.|:||||||:|||||:|:||:||:.||||||..|:|
 Frog   380 HDGFMTGANGEVSFVNIKTLNEWDSRYCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALL 444

  Fly   446 AGSDQLKLGYVSRMNPRDHLRHVILGTQQFKPQEFATQINLNMDNAWGVLRCLIDLVMRQPDGKY 510
            |||:.||||||||.:.:|..|||:||||||||.|||.||||:|:||||:|||::|:.|:..:|||
 Frog   445 AGSEYLKLGYVSRCHVKDSTRHVVLGTQQFKPNEFANQINLSMENAWGILRCVVDICMKLDEGKY 509

  Fly   511 LIMKDPNKPMIRLYDVPENAF-----DSDGDEEEE 540
            ||:|||||.:||:|.:|:..|     |.|.|||||
 Frog   510 LILKDPNKQVIRIYSLPDGTFSSDEEDDDDDEEEE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3d2	NP_731675.1	eIF-3_zeta	7..525	CDD:282888	285/531 (54%)
eif3d	NP_989075.1	eIF-3_zeta	4..524	CDD:368281	285/531 (54%)
		RNA gate. /evidence=ECO:0000250|UniProtKB:K7IM66	288..302		9/13 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..552		9/19 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	622	1.000	Domainoid score	I179
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	647	1.000	Inparanoid score	I793
OMA	1	1.010	-	-		QHG53861
OrthoDB	1	1.010	-	-		D1030308at2759
OrthoFinder	1	1.000	-	-		FOG0004086
OrthoInspector	1	1.000	-	-		otm48258
Panther	1	1.100	-	-	O	PTHR12399
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R379
SonicParanoid	1	1.000	-	-		X2834
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.110