DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpn and tecta

DIOPT Version :9

Sequence 1:	NP_731674.1	Gene:	Cpn / 41474	FlyBaseID:	FBgn0261714	Length:	864	Species:	Drosophila melanogaster
Sequence 2:	XP_009300199.1	Gene:	tecta / 561355	ZFINID:	ZDB-GENE-110411-120	Length:	2201	Species:	Danio rerio

Alignment Length:	152	Identity:	29/152 - (19%)
Similarity:	48/152 - (31%)	Gaps:	53/152 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   580 NEAVASPEVAVAPITAPEPIPEPE--------PSLAT---PTEPIPVEAPVVIQEAVDAVEVPVT 633
            |::....||..|.:......|..|        ..|||   .|.|.|.|:...:.:.:..:...|
Zfish   693 NDSCGEGEVCAAEVGLLGCYPRREAICSLSQSQILATFDGSTMPFPDESSFYLVKTLGRLPANV- 756

  Fly   634 ETSTSIPETTVEYPVAEKVLDPAIT------------EAPVTTQEPDVANINDGAPATEITTPAV 686
                    |:||..:..|:::...|            ||.:...:.|:..:| |.||
Zfish   757 --------TSVEVKIGRKLVNKGPTWLRPVVVRVGHLEAQIGGSDFDLIKVN-GEPA-------- 804

  Fly   687 EIVTAAAEVSDTAIPLIDPPVP 708
                        .:|.:.|..|
Zfish   805 ------------IVPYVHPVEP 814

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpn	NP_731674.1	rne	<9..167	CDD:236766
		rne	<109..300	CDD:236766
		rne	<228..409	CDD:236766
		rne	<331..594	CDD:236766	4/13 (31%)
		rne	<501..763	CDD:236766	29/152 (19%)
tecta	XP_009300199.1	NIDO	100..256	CDD:214712
		VWD	324..480	CDD:278521
		C8	519..594	CDD:214843
		TIL	597..650	CDD:280072
		VWD	717..875	CDD:214566	23/128 (18%)
		C8	913..989	CDD:214843
		TIL	992..1046	CDD:280072
		VWD	1102..1265	CDD:295339
		C8	1349..1420	CDD:285899
		TIL	1424..1477	CDD:280072
		VWC	1479..1532	CDD:302663
		VWD	1539..1690	CDD:278521
		C8	1732..1803	CDD:214843
		ZP	1850..2102	CDD:214579
		Zona_pellucida	1982..2102	CDD:278526
		FXa_inhibition	2132..2166	CDD:291342
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900