DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpn and cv-2

DIOPT Version :9

Sequence 1:	NP_731674.1	Gene:	Cpn / 41474	FlyBaseID:	FBgn0261714	Length:	864	Species:	Drosophila melanogaster
Sequence 2:	NP_524809.2	Gene:	cv-2 / 45280	FlyBaseID:	FBgn0000395	Length:	751	Species:	Drosophila melanogaster

Alignment Length:	136	Identity:	34/136 - (25%)
Similarity:	43/136 - (31%)	Gaps:	52/136 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 PETP-----ALAPVVAE------SQVAANTVVATPPTPAPEPET-----IAPPVVAETPEV-ASV 344
            ||.|     .:|.||.|      ||...|.:  .||.|.....|     |....|||..|| ||:
  Fly   139 PEDPCKTYKCVATVVTETIQKCYSQCDNNQL--QPPRPGECCPTCQGCKINGQTVAEGHEVDASI 201

  Fly   345 --------------AVAETTPPVVPPVAAESIPAPVVATTPVPATLAVTDPDVTASAVPELPPVI 395
                          ..::.|.||:                |.|.:..:..||   ...|..|...
  Fly   202 DDRCLVCQCRGTQLTCSKKTCPVL----------------PCPMSKQIKRPD---ECCPRCPQNH 247

  Fly   396 APSPVP 401
            :..|||
  Fly   248 SFLPVP 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpn	NP_731674.1	rne	<9..167	CDD:236766
		rne	<109..300	CDD:236766	2/2 (100%)
		rne	<228..409	CDD:236766	34/136 (25%)
		rne	<331..594	CDD:236766	19/86 (22%)
		rne	<501..763	CDD:236766
cv-2	NP_524809.2	VWC	184..243	CDD:214564	16/77 (21%)
		VWC	256..310	CDD:278520
		VWC	319..376	CDD:214564
		VWD	371..536	CDD:214566
		C8	580..646	CDD:285899
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900