DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cpn and Kcp

DIOPT Version :9

Sequence 1:NP_731674.1 Gene:Cpn / 41474 FlyBaseID:FBgn0261714 Length:864 Species:Drosophila melanogaster
Sequence 2:XP_011239372.1 Gene:Kcp / 333088 MGIID:2141640 Length:2120 Species:Mus musculus


Alignment Length:625 Identity:122/625 - (19%)
Similarity:171/625 - (27%) Gaps:222/625 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 VAAPTPPAA--SPVSTPPVAVAQIPVAVSAPVAPPVAATPTPVA----------PI--------P 130
            :|...||.:  .||.||.....|.|   .||...|.:....||.          |.        .
Mouse   667 LARRCPPLSCPQPVLTPGDCCPQCP---DAPADCPQSGNMVPVRHQEHFFQPGDPCSRCLCLDGS 728

  Fly   131 VAAPVIATPPVAASAPTPAAVTPVVSPVIATPPVVPANTTVPVAAPVAAVPAAVPVVAPVLAPAV 195
            |:...:..||...:.|...|..|.....:.......:....|                   :|.|
Mouse   729 VSCQRLTCPPAPCAHPRRDACCPSCDGCLYQGKEFASGERFP-------------------SPNV 774

  Fly   196 APAV-----APVVAE--TPAPPPVAEIPVATIPECVAPLIPEVSVVATKPLAAAE---------- 243
            |..|     ..|..|  |.||   |:.|..|..:| .|.......:....|::.|          
Mouse   775 ACHVCLCWEGSVKCEPRTCAP---AQCPFPTREDC-CPACDSCDYLGVSYLSSQEFPDPREACNL 835

  Fly   244 -------------PVVVAPPATETPVVAPAAASP-------HVSVAPAVETAVVAPVSASTEPPV 288
                         |  ..|||...|::.|....|       |...|...||.        .:|..
Mouse   836 CTCLGGFVTCTRRP--CEPPACSHPLIVPEHCCPTCQGCLYHGITAALGETL--------PDPLD 890

  Fly   289 AAATLTTAPE-------TPALAPVVAESQVAANTVVATPPTPA--PEPETIAPPVVA-------- 336
            ...:|.|..|       .|.                  ||.|.  |.|.....||..        
Mouse   891 PTCSLCTCEEGSMRCQKKPC------------------PPAPCAHPSPGPCFCPVCRSCLSQGRE 937

  Fly   337 -------ETPEVASVAVAETTPPVVPPVAAESIPAPVVATTPVPATLAVTDPDVTASAVPELPPV 394
                   |.||    ...|....:...|:...:..|     .:|....||:|   .:..|.....
Mouse   938 HQDGEEFEGPE----GSCERCRCLAGQVSCTRLQCP-----SLPCLHQVTEP---GTCCPRCTGC 990

  Fly   395 IAPSPVPSAVAETPVDLAPPVLPPVAAEPVPAVVAEETPETPA--PASAPVT--------IAALD 449
            :|.                               .||.||..:  ||.:|.:        |....
Mouse   991 LAR-------------------------------GEEHPEGSSWVPADSPCSSCMCHKGIITCAQ 1024

  Fly   450 IPEVAPVIAAPSDAPAEAPSAAAPIVS--TPPTTASVPETTAPPAAVPTEPIDVSVLSEAAIETP 512
            :..|:..|     .|.|.||...|..|  ........|..:..|.|   :|.:|.:..|.| :.|
Mouse  1025 VQCVSACI-----WPQEGPSDCCPQCSGCEHGGRKYEPGESFQPGA---DPCEVCICKEQA-DMP 1080

  Fly   513 VAPPVEVTTEVAVADVAPPEAAADLIIEPV----------EPPAPIPDLLEQTTSVPAVEAAEST 567
            .||     .::.||| ..|.|...|....:          .....:|.......|.||..||...
Mouse  1081 TAP-----KDMGVAD-RYPGAREQLAFHSLGLSSVHSCCSRSVRGLPAFTVVGGSAPAWWAAHQA 1139

  Fly   568 SSPI--PETSLPP-PNEAVASPEVAVAPITAPEPIPEPEP 604
            |..:  |.|::|| |.:|:::   ....:...|.:| |:|
Mouse  1140 SFFLLAPSTAVPPVPVKALSN---CTEDLVGSELVP-PDP 1175

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CpnNP_731674.1 rne <9..167 CDD:236766 21/100 (21%)
rne <109..300 CDD:236766 44/252 (17%)
rne <228..409 CDD:236766 37/234 (16%)
rne <331..594 CDD:236766 59/302 (20%)
rne <501..763 CDD:236766 29/117 (25%)
KcpXP_011239372.1 VWC 166..220 CDD:278520
VWC 224..280 CDD:327433
VWC 285..341 CDD:327433
VWC 344..399 CDD:327433
VWC 458..514 CDD:278520
VWC 517..573 CDD:327433
VWC 634..690 CDD:327433 7/22 (32%)
VWC <717..753 CDD:327433 7/35 (20%)
VWC 931..987 CDD:327433 11/67 (16%)
VWC <1173..1214 CDD:214564 2/3 (67%)
VWC 1221..1278 CDD:214564
VWD 1285..1432 CDD:365869
C8 1482..1549 CDD:370094
Glutenin_hmw <1757..>1975 CDD:367362
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1216
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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