DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cpn and Kcp

DIOPT Version :9

Sequence 1:NP_731674.1 Gene:Cpn / 41474 FlyBaseID:FBgn0261714 Length:864 Species:Drosophila melanogaster
Sequence 2:XP_038964921.1 Gene:Kcp / 296952 RGDID:1561119 Length:1671 Species:Rattus norvegicus


Alignment Length:701 Identity:144/701 - (20%)
Similarity:187/701 - (26%) Gaps:235/701 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    84 PVVAAPTPPAASPV------------STPPVAVAQIPVAVSAPVAPPVAATPTPVAPIPVAAPVI 136
            |..|.|.|....||            |..||. :|.|.:........|...|.|..|.|...|  
  Rat   388 PYPARPLPGTCCPVCDGCFLNGREHSSGEPVG-SQDPCSSCHCANGSVQCEPLPCPPAPCRYP-- 449

  Fly   137 ATPPVAASAPTPAAVTPVVSPVIATPPVVPANTTVPVAAPVAAVPAAVPVVAPVLAPAV-APA-- 198
                    ...|....||..  :..|||...||.      ...:.|..|:.:..:|.|. |||  
  Rat   450 --------GRIPGQCCPVCD--VPCPPVQAVNTR------DMNIGARRPLPSKRMAAAFGAPARL 498

  Fly   199 -VAPVVAETPAPPPVAEIPVATIPECVAPLIPEVSVV--ATKPLAAAEPVVVAPPATETPVVAPA 260
             ..||...|...|||:.:|.|  |....|:...|..:  .:.......||:..|..||.     .
  Rat   499 VKYPVRNRTARSPPVSTLPPA--PSSAQPVCSMVRSLLRGSSGSQMTSPVLPVPAKTEC-----L 556

  Fly   261 AASPHVSVAPAVETAVVAPVSASTEPPVAA---ATLTTAPETPALAP------------------ 304
            .|..|.::..........||||..:|..:.   .|||:.|...|..|                  
  Rat   557 CAGLHFALQYPANILPSRPVSAQPDPVFSGFDQPTLTSLPHLGACCPSCESCTYHGLVYSNGQNF 621

  Fly   305 ---------VVAESQVAANTVVATPPTPAPEPETIAPPVVAETP----EVASVAVAETTPPVVPP 356
                     ...|......:|:..|.....:|:........:.|    |.......|..|....|
  Rat   622 TDVDSPCQTCYCEDGTVRCSVINCPSLTCAKPQNGPGQCCPKCPDCILEAQMFVDGERFPHPRDP 686

  Fly   357 V---------------AAESIPAPVVATTPVPATLA----------------------VTDP--- 381
            .               |..|.|    ...|:|:|..                      .|||   
  Rat   687 CQECLCQEGQTHCQLRACHSAP----CGHPLPSTCCRNDCKGCAFGGKEYLNGADFPHPTDPCRM 747

  Fly   382 ------DVTASAVPELPPVIAPSPVPSAVAETPVDLAP--PVLP---PVAAEPV----------- 424
                  :|...| ...||:..|.||     .||.|..|  |..|   |.:...|           
  Rat   748 CRCLSGNVQCLA-RRCPPLACPQPV-----LTPGDCCPQCPDAPAGCPQSGNTVLVRHQEHFFQP 806

  Fly   425 -----------PAVVAEETPETPAPASAPVTIAA-------------------LDIPEVAPVIAA 459
                       .:|..:..|..|||.:.|...|.                   ...|.|...:..
  Rat   807 GDPCSRCLCLDGSVSCQRLPCPPAPCAHPRQGACCPSCDGCLYHGKEFANGERFPSPSVTCHVCL 871

  Fly   460 PSDAPAEA-PSAAAPIVSTPPTTASVPETTAPPAAVPTEPIDVSVLSEAAIETPVAPPVEVTTEV 523
            ..:..... |.|.||.....||     .....||....|.:.||.|:..  |.|           
  Rat   872 CWEGSVNCEPRACAPAQCPFPT-----REDCCPACDSCEYLGVSYLNSQ--EFP----------- 918

  Fly   524 AVADVAPPEAAADLII----------EPVEPPAPIPDLLEQTTSVPAVEAA--ESTSSPIPETSL 576
                  .|..|.:|..          .|.||||....|:......|..:..  ...::.:.|| |
  Rat   919 ------DPREACNLCTCLGGFVTCTRRPCEPPACSHPLILPKHCCPTCQGCLYHGITAALGET-L 976

  Fly   577 PPPNEAVASPEVAVAPITAPE--------PIPEPEPSLATPTEPIPVEAPV 619
            |.|.:...|      ..|..|        |.|   |:|.|...|.|...||
  Rat   977 PDPLDPTCS------LCTCEEGSMRCHKKPCP---PALCTHPSPGPCFCPV 1018

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CpnNP_731674.1 rne <9..167 CDD:236766 23/94 (24%)
rne <109..300 CDD:236766 48/199 (24%)
rne <228..409 CDD:236766 45/262 (17%)
rne <331..594 CDD:236766 68/371 (18%)
rne <501..763 CDD:236766 32/139 (23%)
KcpXP_038964921.1 VWC 227..281 CDD:278520
VWC 285..341 CDD:327433
VWC 405..460 CDD:327433 13/65 (20%)
VWC 608..664 CDD:327433 4/55 (7%)
VWC 725..781 CDD:327433 14/61 (23%)
VWC 1022..1078 CDD:327433
VWC 1139..1204 CDD:327433
VWC <1223..1264 CDD:327433
VWC 1271..1328 CDD:327433
VWD 1335..1484 CDD:395046
C8 1527..1599 CDD:214843
TIL 1610..1663 CDD:410995
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1216
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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