DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpn and C16E9.1

DIOPT Version :9

Sequence 1:	NP_731674.1	Gene:	Cpn / 41474	FlyBaseID:	FBgn0261714	Length:	864	Species:	Drosophila melanogaster
Sequence 2:	NP_509176.2	Gene:	C16E9.1 / 182693	WormBaseID:	WBGene00015865	Length:	565	Species:	Caenorhabditis elegans

Alignment Length:	298	Identity:	60/298 - (20%)
Similarity:	87/298 - (29%)	Gaps:	115/298 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   512 PVAPPVEVTTEVAVADVAPPEAAADLIIEPVEPPAPIPDLLEQTTSVPAVEAAESTSSPIPETSL 576
            |..||          ...||       :.|.:||...||....||..||
Worm    29 PYNPP----------GYMPP-------MPPTDPPGYDPDSTFDTTPTPA---------------- 60

  Fly   577 PPPNEAVASPEVAVAPITAPEPIPEPEPSLATPTEPIPVEA--------PVVIQEAVDAVEVPVT 633
             ||:..:.:|           |:|:       .|:.||.|:        .||:...:|:   .|.
Worm    61 -PPSNGLRAP-----------PMPK-------WTQEIPKESSGQQLKIEDVVVGNNIDS---HVE 103

  Fly   634 ETSTSIPETTVEYPVAEKVLDPAITEAPVTTQEPDVANINDGAPATEITTPAV-EIVTAAAEVSD 697
            |.:.|               ....||...:..:.......|.:.|...:.|.: :.:.:.|||..
Worm   104 EVNGS---------------GSGDTEGSGSGDKSGTEESFDASGAQGDSLPDIMKAMDSEAEVLG 153

  Fly   698 TAIP-----LIDPPVPQEIAVAEIPETETKPAEVIVEQSTIPIEAPV------PEVSKYAEPVIS 751
            ...|     :||               .|.....|.||....||..|      |.|......|.|
Worm   154 VNCPSDIIFVID---------------ATSSVRGIFEQYITYIEKVVEGLDVQPTVDHVGAIVYS 203

  Fly   752 EAPAAEVPITAGDNPDNTSVGISEVVPTIAEKAVEEVP 789
            ........|..|::.|..|:          .|||:|:|
Worm   204 SEKKQRTKIKLGEHKDRGSL----------VKAVDELP 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpn	NP_731674.1	rne	<9..167	CDD:236766
		rne	<109..300	CDD:236766
		rne	<228..409	CDD:236766
		rne	<331..594	CDD:236766	17/81 (21%)
		rne	<501..763	CDD:236766	52/270 (19%)
C16E9.1	NP_509176.2	VWA_integrin_invertebrates	158..315	CDD:238753	22/99 (22%)
C16E9.1	NP_509176.2	VWA	391..555	CDD:278519
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900