DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpn and BMPER

DIOPT Version :9

Sequence 1:	NP_731674.1	Gene:	Cpn / 41474	FlyBaseID:	FBgn0261714	Length:	864	Species:	Drosophila melanogaster
Sequence 2:	NP_001352237.1	Gene:	BMPER / 168667	HGNCID:	24154	Length:	685	Species:	Homo sapiens

Alignment Length:	86	Identity:	20/86 - (23%)
Similarity:	29/86 - (33%)	Gaps:	6/86 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   394 VIAPSPVPSAV-AETPVD---LAPPVLPPVAAEPVPAVVAEE-TPETPAPASAPVTIAALD-IPE 452
            |:..|.|...| .:.|::   :..|..|....|.|.....|| .||.........|..... :.|
Human   137 VVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVRE 201

  Fly   453 VAPVIAAPSDAPAEAPSAAAP 473
            |.|:::.|.......|....|
Human   202 VCPILSCPQHLSHIPPGQCCP 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpn	NP_731674.1	rne	<9..167	CDD:236766
		rne	<109..300	CDD:236766
		rne	<228..409	CDD:236766	4/15 (27%)
		rne	<331..594	CDD:236766	20/86 (23%)
		rne	<501..763	CDD:236766
BMPER	NP_001352237.1	VWC	166..224	CDD:278520	13/57 (23%)
		VWC	301..357	CDD:327433
		VWD	364..508	CDD:306577
		C8	560..624	CDD:312319
		TIL	629..682	CDD:307783
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900