DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and BTN1A1

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001723.2	Gene:	BTN1A1 / 696	HGNCID:	1135	Length:	526	Species:	Homo sapiens

Alignment Length:	288	Identity:	59/288 - (20%)
Similarity:	92/288 - (31%)	Gaps:	111/288 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 PPTIDDYQTIISQAGTHAYLPCNVKQLVKK---PISWLRM---------RDGHILTVDQ------ 236
            ||     :.|::..|..|.|||.:......   .:.|.|.         |||.....:|
Human    34 PP-----EPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSPAVLVHRDGREQEAEQMPEYRG 93

  Fly   237 -TTFIADQRFQSVFSPNPERWSLQIKYVQLKDEGTYECQVSTEPK-ASAIVHLRIV----EPKTE 295
             .|.:.|...:.       |.:|:|:.|::.|:|.|.|....:.. ..|:|||::.    :|...
Human    94 RATLVQDGIAKG-------RVALRIRGVRVSDDGEYTCFFREDGSYEEALVHLKVAALGSDPHIS 151

  Fly   296 LIGESTRHVKAGSQVKLRCIISQALEPPLFINWFYNQKQIYLHNRRGWRTEIERIDLPAEVPTTS 360
            :      .|:...::.|.|         ..:.| |.:.|:.      ||
Human   152 M------QVQENGEICLEC---------TSVGW-YPEPQVQ------WR---------------- 178

  Fly   361 TTTTTTTTTASTTTTTTSTTPATPSTTATGSTEGATSSETLN----GLVTITRSYILDAISQNDV 421
                            ||.....|||           ||:.|    ||.|:..|.|:...|..:|
Human   179 ----------------TSKGEKFPST-----------SESRNPDEEGLFTVAASVIIRDTSAKNV 216

  Fly   422 S------ELGAAAGVAVATETSTAQLLT 443
            |      .||....|.::...|:...||
Human   217 SCYIQNLLLGQEKKVEISIPASSLPRLT 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	26/111 (23%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	25/105 (24%)
BTN1A1	NP_001723.2	IG_like	35..141	CDD:214653	27/117 (23%)
		Ig_MOG_like	43..142	CDD:143190	25/105 (24%)
		Ig	162..223	CDD:299845	23/119 (19%)
		SPRY_PRY_BTN1_2	302..473	CDD:293991
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..526
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910