DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and cadm2b

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_005157530.1	Gene:	cadm2b / 571698	ZFINID:	ZDB-GENE-080506-3	Length:	441	Species:	Danio rerio

Alignment Length:	169	Identity:	45/169 - (26%)
Similarity:	67/169 - (39%)	Gaps:	28/169 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 TRRPVATTTLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTF--- 239
            |:..|..:..:.|.|    |.:....|:.|.:.|.|.......:.|..       ...||.|
Zfish    24 TKNKVKGSQAQFPIT----QNVTVVEGSTANMTCRVDYNDNTSLQWSN-------PAQQTLFFGD 77

  Fly   240 ---IADQRFQSVFSPNPERW---SLQIKYVQLKDEGTYECQVSTEPKASAIVHLRI--VEPKTEL 296
               :.|.|.:.|.:    .|   ::.|..|.|.|||.|.|.:.|.|..::...|.:  |..|.|:
Zfish    78 KKALRDNRIELVRA----SWKELTISISDVALSDEGQYTCSLFTMPVKTSKAFLTVLGVPAKPEI 138

  Fly   297 IGESTRHVKAGSQVKLRCIISQALEPPLFINWFYNQKQI 335
            .|.| |..:.|..|.|.|..|.: :|...|.||.|.|::
Zfish   139 TGLS-RPAQEGEDVTLTCTTSGS-KPAADIRWFRNDKEV 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	24/100 (24%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	23/96 (24%)
cadm2b	XP_005157530.1	Ig	35..129	CDD:299845	26/108 (24%)
		IG_like	39..129	CDD:214653	24/100 (24%)
		Ig	151..230	CDD:299845	10/26 (38%)
		I-set	234..320	CDD:254352
		IGc2	247..310	CDD:197706
		4.1m	363..381	CDD:128590
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910