DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and igsf9bb

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	434	Identity:	93/434 - (21%)
Similarity:	136/434 - (31%)	Gaps:	162/434 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 DDYQTIISQAGTHAYLPCN-VKQLVKKP--ISWLRMRDGHILTVDQTTFIADQRFQSVFSP--NP 253
            ::.|.:.|:||....|.|: |..|..:|  :.|.:..       ....|..:.||   :.|  :|
Zfish    28 EEPQFVTSRAGETVILGCDVVHPLNGQPYVVEWFKFG-------VPIPFFINFRF---YPPHVDP 82

  Fly   254 E---------RWSLQIKYVQLKDEGTYECQVSTEPKASAIVHLRIVEPKTELIGESTRHVKAGSQ 309
            |         :.||:|:.|:.:|:|.|||:|                    |:.|...|.
Zfish    83 EYAGRASLHGKSSLRIERVRSEDQGWYECKV--------------------LMLEQQYHT----- 122

  Fly   310 VKLRCIISQALEPPLFINWFYNQKQIYLHNRRGWRTEIERIDLPAEVPTTSTTTTTTTTTAST-- 372
                                       .|| ..|      :.|....|.|.|.|......|..
Zfish   123 ---------------------------FHN-GSW------VHLTVNAPPTFTDTPPQYVEAKEGG 153

  Fly   373 TTTTTSTTPATPSTTATGSTEG-----ATSSETLNGLVTITRSYILDAISQND--------VSEL 424
            :.|.:.|....|..:.:...||     :|..:..:|.:|:.      :||:.|        .||.
Zfish   154 SITLSCTAFGNPKPSVSWLREGNPVQDSTKYKVSDGSLTLV------SISREDRGAYTCRAYSEQ 212

  Fly   425 GAAAGVAVATETSTAQLLTEVEATSSTSGTSTGAGLLASTSAAYAAGAAAGITTAATGDSAATAA 489
            |.|        ..|.:||.:                    ...:.......||...:.|:
Zfish   213 GEA--------VHTTRLLVQ--------------------GPPFIVSPPENITVNISQDA----- 244

  Fly   490 TTSAWLTTMDAEAATTAATTTTTMLPSSSFIKQ--------ITTASLIIPAVVKLDSGNYTCSPS 546
                 ..|..|||.....|.|......:.|.|.        :...||||..|...|:|.||||||
Zfish   245 -----FFTCQAEAYPGNLTYTWFWEEDNVFFKNDLKRRVSILIDGSLIISQVKPEDAGKYTCSPS 304

  Fly   547 NSAPRT------IVLHVLNGEYSASAIKSGSVSWSALIGCHGYL 584
            ||..|.      :.:|     |.|..|....|.:.| ||..||:
Zfish   305 NSLGRPPSASAYLTVH-----YPARVINMPPVIYVA-IGLPGYI 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	26/105 (25%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	23/99 (23%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653	25/92 (27%)
		Ig	41..113	CDD:143165	21/81 (26%)
		IG_like	144..223	CDD:214653	18/92 (20%)
		IGc2	151..208	CDD:197706	11/62 (18%)
		I-set	227..319	CDD:254352	27/101 (27%)
		Ig	<263..319	CDD:299845	18/55 (33%)
		Ig_2	326..414	CDD:290606	7/18 (39%)
		IG_like	329..403	CDD:214653	6/15 (40%)
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910