DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and lrrn1

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001124166.1	Gene:	lrrn1 / 568527	ZFINID:	ZDB-GENE-071126-1	Length:	717	Species:	Danio rerio

Alignment Length:	187	Identity:	38/187 - (20%)
Similarity:	68/187 - (36%)	Gaps:	32/187 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 SLQIKYVQLKDEGTYECQV-STEPKASAIVHLRI---VEPKTELIGESTRHVKAGSQVKLRCIIS 317
            :|:|.|:|:.|.|.|.|.. :||...:.:..:|:   :...|:|:....:|.::.|
Zfish   484 TLRISYIQVDDSGHYTCVAQNTEGADTRVTAIRVNGTLLDSTQLMKIYVKHTESHS--------- 539

  Fly   318 QALEPPLFINWFYNQKQIYLHNRRGWRTEIERIDLPAEVPTTSTTTTTTTTTASTTTTTTSTTPA 382
                  :.::|..| ..:...|.: |.:...:||.|      ..|.|............|...||
Zfish   540 ------ILVSWKVN-SNVMTSNLK-WSSATMKIDNP------HITYTAKVPVDVHEYNLTHLQPA 590

  Fly   383 TPSTTATGSTEGATSSETLNGLVTITRSYILDAISQNDVSELGAAAGVAVATETSTA 439
            |........:.  ...:|....|.:|..:...|:   ::||.|....:|....|..|
Zfish   591 TEYEVCLSVSN--IHQQTQKSCVNVTTKHATFAV---EISEQGTNTALAAVMGTILA 642

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	10/32 (31%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	11/36 (31%)
lrrn1	NP_001124166.1	leucine-rich repeat	55..74	CDD:275380
		LRR_RI	86..>276	CDD:238064
		LRR_8	97..156	CDD:290566
		leucine-rich repeat	98..121	CDD:275380
		leucine-rich repeat	122..145	CDD:275380
		leucine-rich repeat	146..169	CDD:275380
		leucine-rich repeat	170..193	CDD:275380
		leucine-rich repeat	194..217	CDD:275380
		LRR_8	216..276	CDD:290566
		leucine-rich repeat	218..241	CDD:275380
		LRR_RI	242..401	CDD:238064
		leucine-rich repeat	242..265	CDD:275380
		LRR_8	264..324	CDD:290566
		leucine-rich repeat	266..289	CDD:275380
		leucine-rich repeat	290..314	CDD:275380
		LRR_8	313..374	CDD:290566
		leucine-rich repeat	315..337	CDD:275380
		leucine-rich repeat	340..353	CDD:275378
		leucine-rich repeat	364..376	CDD:275378
		LRRCT	372..414	CDD:214507
		IG_like	433..517	CDD:214653	10/32 (31%)
		Ig	441..517	CDD:299845	10/32 (31%)
		FN3	532..601	CDD:214495	15/91 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910