DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and igsf9ba

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	605	Identity:	123/605 - (20%)
Similarity:	184/605 - (30%)	Gaps:	243/605 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 DDYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQ-------------RF 245
            ::.|.:.::||....|.|:|               .|.|...||.::.:.             ||
Zfish    28 EEPQFVTARAGESVVLGCDV---------------SHPLNGQQTPYVVEWFKFGVPIPFFINFRF 77

  Fly   246 QSVFSP--NPE---------RWSLQIKYVQLKDEGTYECQV-STEPKASAI-----VHLRIVEPK 293
               :.|  :||         :.||||:.|:.:|:|.|||:| ..|.:....     |||.:..|.
Zfish    78 ---YPPHVDPEYAGRASLHGKASLQIEQVRSEDQGWYECRVLMLEQQYDTFHNGSWVHLTVNAPP 139

  Fly   294 TELIGESTRHVKA--GSQVKLRCIISQALEPPLFINWFYNQKQIYLHNRRGWRTEIERIDLPAEV 356
            | ......::|:|  |..:.|.|..            |.|.|.:..     |..|.:::
Zfish   140 T-FSDTPPQYVEAREGGSITLTCTA------------FGNPKPVVT-----WLREGDQL------ 180

  Fly   357 PTTSTTTTTTTTTASTTTTTTSTTPATPSTTATGSTEGA---TSSETLNG---LVTITRSYILDA 415
              |||...|.:..:.|....|.......|..| .|.:|.   |:...:.|   :||...:..::
Zfish   181 --TSTRKYTVSDGSLTVQAITREDRGAYSCRA-HSDQGEALHTTRLLVQGPPYIVTPPENITVN- 241

  Fly   416 ISQNDVSELGAAAGVAVATETSTAQLLTEVEATSSTSGTSTGAG-------------------LL 461
            ||||                   ||...:.||   ..|..|...                   .:
Zfish   242 ISQN-------------------AQFTCQAEA---YPGNLTYTWYWEEDNVYFKNDLKLRVRIFI 284

  Fly   462 ASTSAAYAAGAA-AGITTAATGDSAATAATTSAWLTT--------------------------MD 499
            ..|...|..... ||..|.:..:|...:.:.||:||.                          :|
Zfish   285 DGTLIIYRVKPEDAGKYTCSPSNSLGISPSASAYLTVQYPARVVNMPPVIYVPRKLSGIIRCPVD 349

  Fly   500 AEAATTAA-------TTTTTMLPSSSFIKQITTASLIIPAVVKLDSGNYTCSPSN-------SAP 550
            |....|:.       .......|..|   |:|..|:.:..|.:...|.|||.|.|       |.|
Zfish   350 ANPPVTSVRWEKDGYPLRIEKYPGWS---QMTDGSIRVAEVTEDSLGTYTCVPYNVLGTMGQSPP 411

  Fly   551 RTIVLH---VLN----GEYSASA----------------------------------IKSGSVSW 574
            .|:||.   ..|    |||...|                                  :.|||:.:
Zfish   412 ATLVLKDPPYFNVRPGGEYRQEAGRELVIPCAASGDPEIPTIQWRKVGKPSRSKHNLLPSGSLQF 476

  Fly   575 SALI-GCHGYLHWRNVSTLLTLLWIIKFALARDICQPNATSKATTRTSLLRAGDGATADVTRETG 638
            .:|. ..||  .|..|:|                   |..:..|..|.|...|          |.
Zfish   477 VSLSKEDHG--EWECVAT-------------------NVVTSITASTRLFVIG----------TS 510

  Fly   639 PKSGASFHRVSSSISATKVA 658
            |.:..:.| ||:|.|:..|:
Zfish   511 PHAPTNVH-VSASTSSANVS 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	30/121 (25%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	28/115 (24%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652	25/102 (25%)
		I-set	139..225	CDD:254352	22/112 (20%)
		I-set	229..321	CDD:333254	21/114 (18%)
		Ig	345..415	CDD:325142	18/72 (25%)
		Ig	438..503	CDD:319273	11/85 (13%)
		FN3	511..606	CDD:238020	7/20 (35%)
		FN3	622..706	CDD:238020
		Atrophin-1	<924..1361	CDD:331285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810