DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and unc5da

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001315278.1	Gene:	unc5da / 566274	ZFINID:	ZDB-GENE-080908-2	Length:	967	Species:	Danio rerio

Alignment Length:	335	Identity:	57/335 - (17%)
Similarity:	108/335 - (32%)	Gaps:	113/335 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 NRSSNNVAINNIS--NNGDQRLRLTAALEANLIMSNRNVQEQHSYRITQDNA-----TSAASIAP 140
            |:|...|.:.:.|  ..|.|.....:|.:.|.::.|.::|...:...|..:.     :....:.|
Zfish   398 NQSEYGVDVIDSSALTGGFQSFSFKSARQGNPLLMNSSMQPDLTVSRTYTSPICFPDSMEKELIP 462

  Fly   141 NGTAFGDAPSIPIGV-------------------APATT------------------------TT 162
            ....|...|.:.:.|                   ||:.|                        |:
Zfish   463 EPALFDPLPDLKVKVHSSFMVSLGVSERAEYHAKAPSQTFPRGVVQEIGGGGGTLGGRGKSQLTS 527

  Fly   163 IDPATTTPTTTTRRTTRRPVATTTLKPPPTIDDY-----QTIISQAGTHAYLPCNVKQLVKKPIS 222
            |.||..:..|..:|..|            |...:     :.::..||....:|...   :::..:
Zfish   528 IQPALISSMTNGKRALR------------TSGVFGHGGGRLVVPNAGVSLLVPHGA---IEEDTT 577

  Fly   223 W-LRMRDGHILTVDQTTFIADQRFQSVFSP-------------------------NPERWSLQIK 261
            | |.|.    :|...::.::|:..:.:.||                         |.|.|::::|
Zfish   578 WELYMS----ITQQDSSALSDEAQEILLSPEVTYGPPGLSLSCPVALTVAHCADVNSEDWNIKLK 638

  Fly   262 YVQLKDEGTYECQVSTEPKASA-------IVHLRIVEPKT-ELIGESTRHVKAGSQVKLRCIISQ 318
            . |.:|....|..:..|...|.       ..||.:..|.. .|:||:.... ||.:::|....:.
Zfish   639 R-QTQDNSWEEVMILEEESTSCYCLLDTQCCHLLVERPGCYALVGEALSQA-AGKRLRLAAFGNM 701

  Fly   319 ALEPPLFINW 328
               .|.|:|:
Zfish   702 ---EPNFLNY 708

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	21/124 (17%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	20/118 (17%)
unc5da	NP_001315278.1	I-set	151..239	CDD:254352
		Ig	153..239	CDD:299845
		TSP1	245..296	CDD:214559
		TSP1	301..349	CDD:214559
		ZU5	543..639	CDD:279170	15/114 (13%)
		Death_UNC5D	855..952	CDD:176779
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910