Protein Alignment dpr15 and robo4

DIOPT Version :9

• Sequence 1: NP_001287299.1
• Gene: dpr15 / 41473
• FlyBaseID: FBgn0037993
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_689255.3
• Gene: robo4 / 560765
• ZFINID: ZDB-GENE-020809-1
• Length: 1134
• Species: Danio rerio
• Alignment Length: 559
• Identity: 106/559 - (18%)
• Similarity: 176/559 - (31%)
• Gaps: 167/559 - (29%)

  Fly   180 RPVATTTLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLR----MRDGHILTVDQTTFI 240
            |....:.|..|..:...:.:..|.|..|...|.........|.|.|    :.:|..|.
Zfish   255 RAARLSVLAKPVLLRKPEDVSVQLGESAQFFCEADGDPMPSIEWSREQGPLPNGRYLI------- 312

  Fly   241 ADQRFQSVFSPNPERWSLQIKYVQLKDEGTYECQVSTEPKASAIVHLRIVEP------------- 292
                       ||:. ||||.||..:|.|.|.|.|..:...|......:||.
Zfish   313 -----------NPDH-SLQIHYVTAQDMGRYSCTVENKLGVSVASAQLLVEDAGGTRLRDLHKEL 365

  Fly   293 ------------------------KTELIGESTRHVKAGSQVKLRCIISQALEPPLFINWFYN-- 331
                                    |.:..| |..|...|.:|..|.::      |...:|...
Zfish   366 SALRVSLENVTVMSTASNMSQVMWKLQSFG-SQPHYLEGFEVLYRSLL------PASSDWTAQRV 423

  Fly   332 -QKQIYLH---NRRGWRTEIE----------------RIDLPAEVPTTSTTTTTTTTTASTTTTT 376
             |..::.|   .:||::.|.:                .:.:|..||:.:....:.|..|....|.
Zfish   424 PQPSLHTHVGPLKRGYKYEFKVRPYGSSLYGRESNTRHLRVPEIVPSAAPQDVSITMPAERNDTV 488

  Fly   377 TSTTPATPSTTATGSTEG-----ATSSETLNGLVTI---TRSYILDAISQNDVSELGAAA--GVA 431
            ..:....|.....|..:|     ..|.|..:...|:   |.|..:..:..:.:..:..||  |..
Zfish   489 HLSWEPPPHDAHNGIIQGYQVWCVESEEQTSFNWTVDSGTHSIEIFTLLPSRLYWVTVAAVNGAG 553

  Fly   432 VATETSTAQLLTE--VEATSSTSGT-----------------STGAGL---LASTSA-------- 466
            |..::...:||.|  :|||...:|.                 |.|..|   |..|:.
Zfish   554 VGVQSDPYKLLIESRLEATPYQTGILSMSHFVSVIKEPVFIGSVGTLLWCVLMITAVFLYRRHIR 618

  Fly   467 -AYAAGAAAGITTAATGD---SAATAATTSAWLTTMDAEAATTAATTTTTMLPS--SSFIKQITT 525
             |..:|.::|:....:.|   ....||..|.|::. .....:.:........||  :|.:::.|
Zfish   619 PANPSGKSSGLYRLESEDLIIKHRMAAPDSPWISG-GWRPGSNSEPKQGLWTPSQENSGLRRTT- 681

  Fly   526 ASLIIPAVVKLDSGNYTCSPSNSA----PRTIVLHVLNGEYSASAIKSGSVSWSALIGC----HG 582
                :|..||.|.     :|..||    |....::   |.:......:|..::::...|    ||
Zfish   682 ----LPITVKKDP-----NPLRSAVPIVPDNCGVY---GTFYVDLTGNGLKTFNSPGRCPRMPHG 734

  Fly   583 YLHWRNVSTLLTLLWIIKFALARDI----------CQPN 611
            ....:|..|:.....|:|.|:.|::          .|||
Zfish   735 NSQLQNSETIRITEPIVKTAVVRELQALPWKRTLPAQPN 773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	23/95 (24%)
		V-set	204..290	CDD:284989	22/89 (25%)
robo4	XP_689255.3	Ig1_Robo	70..169	CDD:143317
		I-set	71..168	CDD:254352
		I-set	175..261	CDD:254352	1/5 (20%)
		Ig2_Robo	177..261	CDD:143201	1/5 (20%)
		I-set	265..350	CDD:254352	24/103 (23%)
		Ig	282..350	CDD:299845	21/86 (24%)
		FN3	373..448	CDD:214495	14/81 (17%)
		FN3	472..560	CDD:238020	15/87 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900