DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and lrit3a

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001122166.1	Gene:	lrit3a / 558559	ZFINID:	ZDB-GENE-080723-63	Length:	636	Species:	Danio rerio

Alignment Length:	297	Identity:	65/297 - (21%)
Similarity:	98/297 - (32%)	Gaps:	84/297 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 PTIDDYQT-IISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRFQSVFSPNPE 254
            ||:....| |.|..|::..|.|:........:.| ...||.::   ..|.:.:...:.|
Zfish   252 PTVMTSATKITSPLGSNVLLRCDANGFPTPTLLW-TTADGSVV---NNTVVQESPGEGV------ 306

  Fly   255 RWS-LQIKYVQLKDEGTYECQV-STEPKASAIVHLRI--VEPKTELIGESTRHVKAGSQVKLRCI 315
            ||| |.:..:..||.|.|.|:. :....|.|.:.|.:  |:|.|..
Zfish   307 RWSILSLHSIVFKDAGDYRCKAKNVAGNAEAYITLSVDGVQPTTPF------------------- 352

  Fly   316 ISQALEPPLFINWFYNQKQIYLHNRRGWRTEIERIDLPAEVPTTSTTTTT----TTTTASTTTTT 376
                  ||:.|.     ||                  |.:.|||:.|.|.    |:.:..|.||.
Zfish   353 ------PPINIT-----KQ------------------PEDQPTTTFTPTKMPLFTSLSPITITTR 388

  Fly   377 TSTTPATPSTTATGSTEG-------------ATSSETLNGLVTITRSYILDAISQNDVSE----L 424
            ...|...|.||......|             |...::.||..:|.:|.|.|.....:.:|    |
Zfish   389 PVMTTMPPLTTRKSPIPGGGVQRSPPAGDKPAKVQQSKNGKGSIKKSDIRDIEVVEETTETAVLL 453

  Fly   425 GAAAGVAVATETSTAQLLTEVEATSSTSGTSTGAGLL 461
            .:|.|:...|..:......:.:....|..|..|.|.|
Zfish   454 WSAEGLPSDTPLTVVYFPYDAKDDKETVDTEVGQGKL 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	23/94 (24%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	20/89 (22%)
lrit3a	NP_001122166.1	LRR_8	81..141	CDD:290566
		leucine-rich repeat	83..106	CDD:275378
		LRR_4	107..145	CDD:289563
		leucine-rich repeat	107..130	CDD:275378
		LRR_8	129..>171	CDD:290566
		LRR_4	129..170	CDD:289563
		leucine-rich repeat	131..154	CDD:275378
		leucine-rich repeat	155..168	CDD:275378
		TPKR_C2	199..249	CDD:301599
		Ig	252..343	CDD:299845	25/100 (25%)
		IG_like	261..343	CDD:214653	22/91 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900