DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and lrit1a

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001018174.2	Gene:	lrit1a / 553943	ZFINID:	ZDB-GENE-040924-5	Length:	643	Species:	Danio rerio

Alignment Length:	308	Identity:	52/308 - (16%)
Similarity:	95/308 - (30%)	Gaps:	91/308 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 FGDAPSIPIGVAPATTTTIDPATTTPTTTTRRTTRRPVATTTLKPPPTIDDYQTIISQAGTHAYL 209
            |..:||:.:..........||.:.:....:....||      .:.|........:.|..|.:..|
Zfish   213 FQKSPSLSVAFIDTRLRCADPESLSGVLFSDAELRR------CQGPRVHTAVARVRSAVGNNVLL 271

  Fly   210 PCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRFQSVFSPNPERWS-LQIKYVQLKDEGTYEC 273
            .|....:....::| |..||..|   ..|.:.:...:.:.      || |.:..|..:|.|.|.|
Zfish   272 RCGTVGVPIPELAW-RRADGKPL---NGTVLLENSKEGIV------WSILSVPAVSYRDTGKYIC 326

  Fly   274 QVST-EPKASAIVHLRI----------VEPKTELIGESTRHVKAGSQVKLRCIISQALEPPLFIN 327
            :.:. ...|.|::.|.|          ::||.:|                     ::.:|...:.
Zfish   327 KATNYAGSAEAVISLIINDAPKMENPTLDPKPKL---------------------KSKKPNTMVK 370

  Fly   328 WFYNQKQIYLHNRRGWRTEIERIDLPAEVPTTSTTTTTTTTTASTTTTTTSTTPATPSTTATGST 392
            ..|.:|.|..:                                 .:.|..:..|.:.:.:.||..
Zfish   371 AAYQEKHIATY---------------------------------VSPTPKNGLPLSGTVSYTGPY 402

  Fly   393 EGATSSETLNGLVTITRSYILDAISQNDVSELGAAAGVAVATETSTAQ 440
            .|..|....|..:. |::...|...:.::|.|        |..||:.|
Zfish   403 PGMESDNAANSRMN-TQTASPDGFLETNLSNL--------AANTSSLQ 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	21/93 (23%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	21/97 (22%)
lrit1a	NP_001018174.2	leucine-rich repeat	61..84	CDD:275378
		LRR_8	63..119	CDD:290566
		LRR_RI	<77..175	CDD:238064
		leucine-rich repeat	85..108	CDD:275378
		LRR_8	108..167	CDD:290566
		leucine-rich repeat	109..132	CDD:275378
		leucine-rich repeat	133..156	CDD:275378
		leucine-rich repeat	157..170	CDD:275378
		LRRCT	199..243	CDD:214507	5/29 (17%)
		I-set	252..343	CDD:254352	22/100 (22%)
		Ig	259..333	CDD:299845	18/83 (22%)
		fn3	448..515	CDD:278470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900