DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and nectin3b

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001014326.1	Gene:	nectin3b / 541491	ZFINID:	ZDB-GENE-050327-14	Length:	574	Species:	Danio rerio

Alignment Length:	424	Identity:	81/424 - (19%)
Similarity:	132/424 - (31%)	Gaps:	149/424 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 PPTIDDYQTIISQAGTHAYLPCNVK---QLVKKPISWLR-MRDGHI-LTVDQTTFIAD-----QR 244
            ||.::      :..|.:..|.|.|:   .|.....||.| :.:|.: |.|....|...     :|
Zfish    42 PPKVN------AVLGKNVTLSCRVQVDTNLSLTQSSWERKLPNGWVTLAVYNPMFGISIPPDYER 100

  Fly   245 FQSVFSPNPERWSLQIKYVQLKDEGTYECQVSTEP----KASAIVHLRIVEPKTELIGESTRHVK 305
            ..|..||:....::.::.|...|.|.|.|:|:|.|    :||..|.: :||||..:...|:..:.
Zfish   101 RLSFRSPSALDATIMLEDVGFADIGVYTCKVATFPLGNTQASTTVSV-LVEPKVYVSAGSSALID 164

  Fly   306 AGSQVKLRCIISQALEPPLFINW---FYNQKQIYLHNRRGWRTEIERIDLPAEVPTTSTTTTTTT 367
            .|::..:...|::...||..::|   .|...:.::..
Zfish   165 GGNETTVATCIAERARPPADVSWETNLYGMSEAHMQE---------------------------- 201

  Fly   368 TTASTTTTTTSTTPATPSTTATGSTEGATSSETLNGLVTITR----------SYILDAISQNDVS 422
             .|:.||||.......||..|.|.|           |..:.:          .||::.....|:.
Zfish   202 -DANGTTTTQVHYIWQPSRHAQGHT-----------LTCVVKHPALQSDFRIPYIINVQFAPDIL 254

  Fly   423 ELGAAAGVAVATETSTAQLLTEVEATSSTSGTSTGAGLLASTSAAYAAGAAAGITTAATGDSAAT 487
            .||......|..|  ..||....:|.                                      .
Zfish   255 VLGYDGDWYVGRE--NVQLKCRAKAN--------------------------------------P 279

  Fly   488 AATTSAWLTTMDAEAATTAATTTTTMLPSSSFIKQITTASLIIPAVVKLDSGNYTCSPSN----- 547
            .|....|: .:|.|....|.....|::    |.:.:.          |.|||.|.|..:|
Zfish   280 PAQHFRWI-RLDGEMPNGAERVNNTLV----FTRPLQ----------KNDSGVYRCEVANDIGLH 329

  Fly   548 ---------------SAPRTIVLHVLNGEYSASA 566
                           :.|.|..:.:|..:.||:|
Zfish   330 SRDIRIRIQDPPSTTTMPPTTPVRLLTADISATA 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	27/105 (26%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	27/99 (27%)
nectin3b	NP_001014326.1	IG_like	42..147	CDD:214653	29/110 (26%)
		Ig1_Nectin-3_like	51..148	CDD:143295	26/97 (27%)
		Ig2_Nectin-3-4_like	151..247	CDD:143328	22/135 (16%)
		IG_like	267..337	CDD:214653	18/124 (15%)
		IGc2	267..327	CDD:197706	18/114 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	442..484
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	498..549
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000