DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr15 and NTM

DIOPT Version :9

Sequence 1:NP_001287299.1 Gene:dpr15 / 41473 FlyBaseID:FBgn0037993 Length:662 Species:Drosophila melanogaster
Sequence 2:NP_001338930.1 Gene:NTM / 50863 HGNCID:17941 Length:367 Species:Homo sapiens


Alignment Length:334 Identity:72/334 - (21%)
Similarity:120/334 - (35%) Gaps:55/334 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   181 PVATTTLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRF 245
            ||.:.....|..:|:   :..:.|..|.|.|.:...|.: ::||..  ..||......:..|.|.
Human    30 PVRSGDATFPKAMDN---VTVRQGESATLRCTIDNRVTR-VAWLNR--STILYAGNDKWCLDPRV 88

  Fly   246 QSVFSPNPERWSLQIKYVQLKDEGTYECQVSTE--PKASAIVHLRI-VEPKTELIGESTRHVKAG 307
             .:.|....::|::|:.|.:.|||.|.|.|.|:  ||.|. |||.: |.||...| .|...:..|
Human    89 -VLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSR-VHLIVQVSPKIVEI-SSDISINEG 150

  Fly   308 SQVKLRCIISQALEPPLFINW---------FYNQKQIYLHNRRGWRTE----------------I 347
            :.:.|.||.:...||.  :.|         |.::.: ||..:...|.:                :
Human   151 NNISLTCIATGRPEPT--VTWRHISPKAVGFVSEDE-YLEIQGITREQSGDYECSASNDVAAPVV 212

  Fly   348 ERIDLPAEVPTTSTTTTTTTTTASTTTTTTSTTPATPSTTATGSTEGATSSETLNGLVTITRSYI 412
            .|:.:....|...:....|........|......|.||.......:.....|...|:....|.::
Human   213 RRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFL 277

  Fly   413 ---------------LDAISQNDVSELGAAAGVAVATETSTAQLLTEVEATSSTSGTSTGAGLLA 462
                           ...::.|.:....|:..:....|.:::.||.||:.|:.|.....||....
Human   278 SKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTLLQEVKTTALTPWKGPGAVSEV 342

  Fly   463 STSAAYAAG 471
            |...:..||
Human   343 SNGTSRRAG 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr15NP_001287299.1 IG_like 197..289 CDD:214653 28/93 (30%)
V-set 204..290 CDD:284989 28/88 (32%)
NTMNP_001338930.1 Ig 44..132 CDD:416386 28/95 (29%)
Ig strand A' 44..49 CDD:409353 0/7 (0%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 0/3 (0%)
FR2 64..70 CDD:409353 1/6 (17%)
Ig strand C 64..70 CDD:409353 1/6 (17%)
CDR2 71..83 CDD:409353 2/13 (15%)
Ig strand C' 72..76 CDD:409353 1/3 (33%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 11/34 (32%)
Ig strand D 87..94 CDD:409353 2/7 (29%)
Ig strand E 97..103 CDD:409353 1/5 (20%)
Ig strand F 110..118 CDD:409353 4/7 (57%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 6/9 (67%)
FR4 125..132 CDD:409353 4/7 (57%)
Ig_3 136..205 CDD:404760 15/72 (21%)
Ig strand A' 142..147 CDD:409353 1/4 (25%)
Ig strand B 153..160 CDD:409353 3/6 (50%)
Ig strand C 166..171 CDD:409353 1/6 (17%)
Ig strand D 177..180 CDD:409353 0/2 (0%)
Ig strand E 184..190 CDD:409353 2/6 (33%)
Ig strand F 197..204 CDD:409353 0/6 (0%)
Ig strand G 211..219 CDD:409353 1/7 (14%)
Ig_3 222..299 CDD:404760 9/76 (12%)
putative Ig strand A 223..229 CDD:409353 0/5 (0%)
Ig strand B 239..243 CDD:409353 1/3 (33%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 0/3 (0%)
Ig strand F 292..297 CDD:409353 0/4 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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