Protein Alignment dpr15 and unc5b

DIOPT Version :9

• Sequence 1: NP_001287299.1
• Gene: dpr15 / 41473
• FlyBaseID: FBgn0037993
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001104619.1
• Gene: unc5b / 494130
• ZFINID: ZDB-GENE-041213-1
• Length: 940
• Species: Danio rerio
• Alignment Length: 613
• Identity: 113/613 - (18%)
• Similarity: 179/613 - (29%)
• Gaps: 214/613 - (34%)

  Fly   106 AALEANLIMSNRNVQEQHSYRITQDNATSAASIAPNGTAFGDAPSIPIGVAPATTTTIDPATTTP 170
            |:|...|::|        |..:...:.:..:.:.|:  :|..||:.|:           |...:.
Zfish    13 ASLLGLLLLS--------STLVIHADGSDYSEVLPD--SFPSAPAEPL-----------PEFQSE 56

  Fly   171 TTTTRRTTRRPVATTTLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHIL--T 233
            .........|||..:....|             .|..|..||.:        |:...| |:.  :
Zfish    57 PEDAFIVKNRPVKLSCKAAP-------------ATQIYFKCNGE--------WVNQND-HVTKES 99

  Fly   234 VDQTTFIADQRFQSVFSPNPERWSLQIKYVQLKDEGT----------YECQ------VSTEPKAS 282
            :|..|                  .|.::.|.:....|          |.||      ..|.....
Zfish   100 LDHIT------------------GLVVREVDISVSRTQVEELFGLEDYWCQCVAWSSAGTTKSRR 146

  Fly   283 AIVHLRIVEP--KTELIGESTRHVKAGSQVKLRCIISQALEPPLFINWFYNQKQIYLHNRRGWRT 345
            |.|.:..:..  :.|.:|   |.|:...:|.|:|...:. .||..::|..|::.|.......:..
Zfish   147 AYVRIAYLRKNFEQEPLG---REVRLEQEVLLQCRPPEG-SPPAEVDWLKNEELIDPALDSNFLI 207

  Fly   346 EIERIDLPAEVPTTSTTTTTTTTTASTTTTTTSTTPATPSTTATGS------------------- 391
            .||. ||..:....|.|...|....:......|:| ||.....:|.
Zfish   208 TIEH-DLIIKQARLSDTANYTCVARNVVAKRRSST-ATLIVYVSGGWSSWTEWSECNAQCGRGWQ 270

  Fly   392 --TEGATSSETLNG----------LVTITRSYILDAISQNDVSELGA------------------ 426
              |...|:...|||          .||.|....:|. ...:.::..|
Zfish   271 RRTRSCTNPAPLNGGAFCDGPPFQRVTCTTLCPVDG-GWTEWAKWSACGTECTHWRSRECQAPPP 334

  Fly   427 ------AAGVAVATETSTAQLL-----TEVEATSSTSGTSTG----AGL---------------- 460
                  .:|..:.::..|..|.     ..||.||...|:.||    |||
Zfish   335 RNGGRHCSGSMMESKNCTEGLCARNKKVSVEHTSHPLGSGTGVAVYAGLVGALLLCVILVLCVGI 399

  Fly   461 -------------LASTSAAYAAGAAAG------------ITTAATGDSAATAAT-----TSAWL 495
                         :..:|:|..|....|            :...|..|..|:|.|     .|...
Zfish   400 LVYRRSCRHLHGEITDSSSALTAAFHPGNYKPPRQDNPHLLHPTAPPDLTASAGTFRGPLFSLQQ 464

  Fly   496 TTMDAEAATTAATTTTTMLPSSSFIK-----QITTASLIIP-AVVKLDSGNYTCSPSNSAPRTIV 554
            .|:|:.  .....||:.:|.....:|     ..|.:||.:| .:..:|....:.....|.|:...
Zfish   465 ATLDSH--HKIPMTTSPLLDPLPSLKIKVYNSSTMSSLELPTGLGSVDGEIMSLKTVGSGPKDHH 527

  Fly   555 LHVLNGEYSASAIKSGSVSWSALIGCHG 582
            .|.|..|.|.||        ||.:|..|
Zfish   528 GHTLPREPSHSA--------SATLGSLG 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	18/109 (17%)
		V-set	204..290	CDD:284989	18/103 (17%)
unc5b	NP_001104619.1	I-set	158..246	CDD:254352	23/93 (25%)
		Ig	160..246	CDD:299845	23/91 (25%)
		TSP1	252..303	CDD:214559	8/50 (16%)
		TSP1	308..356	CDD:214559	3/47 (6%)
		ZU5	538..632	CDD:279170	6/18 (33%)
		Death_UNC5B	853..936	CDD:176780

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910