DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and opcml

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001005580.1	Gene:	opcml / 449538	ZFINID:	ZDB-GENE-040927-3	Length:	342	Species:	Danio rerio

Alignment Length:	346	Identity:	83/346 - (23%)
Similarity:	127/346 - (36%)	Gaps:	79/346 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 PPPTIDDY--QTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRFQSVFSP 251
            |..:.|.|  ..|..:.|..|.|.|::...|.: ::||          ::||.:        |:.
Zfish    30 PARSGDSYLKDNITVRQGDSAVLKCSMDNKVSR-VAWL----------NRTTIL--------FTG 75

  Fly   252 NPERWSL----------------QIKYVQLKDEGTYECQVSTEPK-ASAIVHLRIVEPKTELIGE 299
            | |:|||                :|..|.|.|||.|.|.:.|..| .|..||| ||:....::..
Zfish    76 N-EKWSLDPRVVLLNTAVNEYSIKILNVNLYDEGPYVCSILTNKKPESTKVHL-IVQVPARIVNV 138

  Fly   300 STR-HVKAGSQVKLRCIISQALEPPLFINWFYNQKQIYLHNRRGWR--TEIERIDLPAEVPTTS- 360
            ||. .|..||.|.|.|:.....||.:.  |.:       .:.:|.|  ||.|.:::.......|
Zfish   139 STDVSVNEGSNVSLMCLAIGRPEPSIL--WKF-------RSSKGNRIVTEGEYVEMTGITKDMSG 194

  Fly   361 -----TTTTTTTTTASTTTTTTSTTPATPSTTATGSTEGATSSETLNGLVTITRSYILDAISQND 420
                 |:...:.....|...|.:..|......:||:..|.      .|::....|.:..|..|..
Zfish   195 SYDCITSNDISPPDVRTVQVTVNYPPVISRARSTGTAVGQ------KGVLWCEASAVPLADFQWF 253

  Fly   421 VSE---LGAAAGVAVATETSTAQLLTEVEATSSTSG--TSTGAGLLASTSAA---YAAGAAAGIT 477
            ..|   |....||.:..: ....:||....:....|  |......|..|:|:   |..||...:
Zfish   254 KGERRILNGFNGVKIENK-GKQSMLTFFNVSEEDYGNYTCVAINTLGITNASIILYGPGAIHDV- 316

  Fly   478 TAATGDSAATAATTSAWLTTM 498
                 ::||.:.|.|..|.|:
Zfish   317 -----NNAALSPTCSLLLLTL 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	30/108 (28%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	29/102 (28%)
opcml	NP_001005580.1	Ig	41..129	CDD:299845	30/108 (28%)
		IG_like	41..129	CDD:214653	30/108 (28%)
		IG_like	139..216	CDD:214653	19/85 (22%)
		IGc2	146..202	CDD:197706	15/64 (23%)
		I-set	219..307	CDD:254352	19/94 (20%)
		ig	223..307	CDD:278476	18/90 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810