DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr15 and cadm2

DIOPT Version :9

Sequence 1:NP_001287299.1 Gene:dpr15 / 41473 FlyBaseID:FBgn0037993 Length:662 Species:Drosophila melanogaster
Sequence 2:XP_031751706.1 Gene:cadm2 / 448238 XenbaseID:XB-GENE-998536 Length:441 Species:Xenopus tropicalis


Alignment Length:371 Identity:78/371 - (21%)
Similarity:117/371 - (31%) Gaps:98/371 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   197 QTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRFQSVFSPNPERW---SL 258
            |.:....|....|.|.|.|.....:.|..... ..|..|....:.|.|.:.|.:    .|   |:
 Frog    38 QNVTVVEGGTINLTCRVDQNDNTSLQWSNPAQ-QTLYFDDKKALRDNRIELVRA----SWHELSI 97

  Fly   259 QIKYVQLKDEGTYECQVSTEPKASAIVHLRIV-EPKTELIGESTRHVKAGSQVKLRCIISQALEP 322
            .|..|.|.|||.|.|.:.|.|..::..:|.:: .|:...|...|..|..|..::|.| .|...:|
 Frog    98 SISDVSLSDEGQYTCSLFTMPVKTSKAYLMVLGVPENPHISGFTSPVMEGDTIQLTC-KSSGSKP 161

  Fly   323 PLFINWFYNQKQIYLHNRRGWRTEIERIDLPAEVPTTSTTTTTTTTTASTTTTTTSTTPATPSTT 387
            ...|.||.|.::|         |::::|.                                 ...
 Frog   162 AADIRWFKNDQEI---------TDVQKIQ---------------------------------QQD 184

  Fly   388 ATGSTEGATSSETLNGLVTITRSYILDAISQNDVSELGAAAGVAVATE--TSTAQL---LTEVEA 447
            :.|.|...|||                .:.|.|..:.||.....|..|  |||.|:   :.|:..
 Frog   185 SNGKTFTVTSS----------------LVFQGDRKDDGAVIRCRVDHESLTSTPQIAKQVLEIHY 233

  Fly   448 TSSTSGTSTGAGLLASTSAAYAAGAAAGITTAATGDSAATAATTSAWLTTMDAEAATTAATTTTT 512
            |.:..       :|.||... ..|....:...:.|.......     |.|.|..........|  
 Frog   234 TPTVR-------ILPSTPLP-QEGQPLILICESKGKPLPEPV-----LWTKDGGELPDPERMT-- 283

  Fly   513 MLPSSSFIKQITTASLIIPAVVKLDSGNYTCSPSNSAPRTIVLHVL 558
                      :....|.|..:.|.|:|.|.|..:||..::...:||
 Frog   284 ----------VNGRELTISFLNKTDNGTYRCEATNSIGQSSAEYVL 319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr15NP_001287299.1 IG_like 197..289 CDD:214653 25/94 (27%)
V-set 204..290 CDD:284989 24/88 (27%)
cadm2XP_031751706.1 IgV_1_Necl-3 34..129 CDD:409498 25/95 (26%)
Ig strand B 48..52 CDD:409498 1/3 (33%)
Ig strand C 61..65 CDD:409498 0/3 (0%)
Ig strand E 95..99 CDD:409498 1/3 (33%)
Ig strand F 109..114 CDD:409498 2/4 (50%)
Ig strand G 121..124 CDD:409498 0/2 (0%)
IgI_2_Necl-3 128..231 CDD:409467 31/161 (19%)
Ig strand B 150..154 CDD:409467 1/3 (33%)
Ig strand C 164..168 CDD:409467 1/3 (33%)
Ig strand E 194..198 CDD:409467 2/19 (11%)
Ig strand F 208..213 CDD:409467 0/4 (0%)
Ig strand G 224..227 CDD:409467 0/2 (0%)
IGc2 248..311 CDD:197706 15/79 (19%)
Ig strand B 250..259 CDD:409353 0/8 (0%)
Ig strand C 265..271 CDD:409353 1/10 (10%)
Ig strand C' 274..277 CDD:409353 0/2 (0%)
Ig strand D 280..285 CDD:409353 1/16 (6%)
Ig strand E 286..293 CDD:409353 2/6 (33%)
Ig strand F 300..308 CDD:409353 3/7 (43%)
Ig strand G 311..321 CDD:409353 2/9 (22%)
4.1m 394..412 CDD:128590
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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