DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and klg

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	364	Identity:	78/364 - (21%)
Similarity:	127/364 - (34%)	Gaps:	94/364 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LILLALLICLPAIRGQ---AEETSILNSNGTNGRAFQRTQSRREALIPATTQMAQTLDKASAFRP 71
            ||:::|...|.|..|.   |.|.:|.| .|:|.|:....|....|....|..:.:.|.:...:|.
  Fly    49 LIVISLGWLLHAHAGSGGFAVEAAISN-RGSNSRSMSNVQQSAVAASTLTATLPRFLSRGHTYRA 112

  Fly    72 TMAAALDAAAP-------------NRSSNNVAINNISNNGDQRLRLTAALEANLIMSNRNVQEQH 123
            .:...|  ..|             .|.:|.:..:||....|:|:||....  ||.:|:...|:..
  Fly   113 VVGDTL--VLPCQVENLGNFVLLWRRGTNVLTASNIMVTRDERVRLIDGY--NLEISDLEPQDAG 173

  Fly   124 SY------RITQDNATSAASIAPNGTAFGDAPSIPIGVAPATTTTIDPATTTPTTTTRRTTRRPV 182
            .|      :|.:|...:...:.|        ||:.   |..|:..:......|.|...:.:..||
  Fly   174 DYVCQISDKINRDQVHTVEILVP--------PSVR---AIPTSGQLQARKGGPITLECKGSGNPV 227

  Fly   183 ATTTLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRFQS 247
                    |:|  |.|..|.|..                |..|:.||.|||:::
  Fly   228 --------PSI--YWTKKSGANK----------------STARIGDGPILTLEK----------- 255

  Fly   248 VFSPNPERWSLQIKYVQLKDEGTYECQVSTEPKASAIVHLR--IVEPKTELIGESTRHVKAGSQV 310
                           ::.:..|.|:|...........|.:|  ::.|....:.:|..|...|.:.
  Fly   256 ---------------LERQQAGVYQCTADNGVGDPVTVDMRLDVLYPPDIQVEKSWIHSGEGFEA 305

  Fly   311 KLRCIISQALEPPLFINWFYNQKQIYLHNRRGWRTEIER 349
            ||.||:  ..:|...::|:.|...|...:||...|...|
  Fly   306 KLVCIV--FADPVATVSWYQNSFPIQSTDRRIMATRANR 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	15/93 (16%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	12/87 (14%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	15/63 (24%)
		IG_like	109..195	CDD:214653	18/89 (20%)
		Ig	118..191	CDD:143165	17/76 (22%)
		IG_like	205..274	CDD:214653	20/120 (17%)
		IGc2	213..273	CDD:197706	20/111 (18%)
		IGc2	301..367	CDD:197706	13/44 (30%)
		FN3	392..486	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810