DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr15 and boi

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001096868.3	Gene:	boi / 31229	FlyBaseID:	FBgn0040388	Length:	1105	Species:	Drosophila melanogaster

Alignment Length:	781	Identity:	148/781 - (18%)
Similarity:	232/781 - (29%)	Gaps:	322/781 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LAKMPRRLILLALLI--------CLPAIR-GQAEETSILNSNGT-------------NGRAFQRT 45
            ||..|.||.|:::.:        ...:|| ..|.:..:|...|:             ||:...::
  Fly   124 LASTPARLALVSIALDVGQGSMGARSSIRWSVAPKNCLLIRCGSVISNPPAIWSFYRNGKKLPQS 188

  Fly    46 QSRREALIPATTQMAQTLDKASAFRPTMAAALDAAAPNRSSNN--VAINNISNNGDQRLRL---- 104
            :     |:|....               |..||......:.|.  ||.|:|:  ||: |||
  Fly   189 E-----LLPGAAG---------------ALVLDTVTAKDAGNYSCVATNSIT--GDE-LRLPQTI 230

  Fly   105 ----------------------------TAALEA--------NLIMSNRNVQEQHSYRITQDNAT 133
                                        |..||.        .:|.|:.||.|.::.|.|
  Fly   231 ELRVDYTDRTPPYFLQRPPIEYSARPGETVVLECPGVGSPRPRVIWSSPNVVEIYNNRST----- 290

  Fly   134 SAASIAPNGTAFGDAP---------SIPIGVAPATTTTIDPATTTPTTTTRRTT--RRPVATTTL 187
                |...|....|..         .:..|:||....||      ..:..:|.|  |.|.||.|.
  Fly   291 ----ILSYGLQITDVKPEDQGSYICMLDNGIAPPIDHTI------KLSVLQRPTILRGPAATLTN 345

  Fly   188 KPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRFQSVFSPN 252
            :..|.:               |.|:.....:..|.||  .:|...|.|... :.|.|
  Fly   346 ESNPLL---------------LDCSASGNPQPDIYWL--INGEDATKDPEA-VVDNR-------- 384

  Fly   253 PERWSLQIKYVQLKDEGTYECQV------STEPKASAIVHLRIVEPKTELIGE------------ 299
                |||:|.||.:..|..:|..      ::|.....:..|.|.....|.:||
  Fly   385 ----SLQLKRVQKRHAGVVQCFAKNILGETSEGNILRVNPLEITGEDDEPLGEVPVWPVHESNTG 445

  Fly   300 -STRHVKAGSQVKL-RCIISQALEPP------------LFINW-----------FYNQKQIYL-- 337
             .|.....||:.|. |.....::.||            :.:.|           |:..:...|
  Fly   446 MGTSSTSGGSKNKSGRRKFKASMVPPSRPNVTRLSDESVMLRWSVPQNSGLQITFFKVQYRMLGD 510

  Fly   338 --HNRRGWRTEIERIDLPAEVPTTSTTTTTTTTTASTTTTTTSTTPATPSTTATGSTEGATSS-- 398
              :.|:.|:|..:.|                                 |...|.||..|..:|
  Fly   511 GKNRRKNWQTTSDNI---------------------------------PYGNAHGSGPGQGNSHW 542

  Fly   399 -------------------ETLNGLVTITRSY---ILDAISQNDVSELGAAAGVAVATETSTAQL 441
                               .::.|| |..:.|   |:...|.||..|...:....:...||.:.|
  Fly   543 RARNRDREYEMGNPPKNFTSSVTGL-TAGKYYRFRIVAVYSNNDNKEGNTSLKFFLQNGTSKSNL 606

  Fly   442 ----LTEVEATSSTSGTSTGAGLLASTS--------AAYAAGAAAGITTAATGDSAATAA----- 489
                |.||| |.|.|.......|::||.        |.|....:|.....||.|...:.:
  Fly   607 PVPELREVE-TLSESAVVLHWSLVSSTQNEDIDGYYAYYRPADSAAEYLKATVDGGMSRSFKIDL 670

  Fly   490 ----TTSAW-LTTMDAEAAT---------------TAATTTTTMLPSSSFIKQ------------ 522
                |...: |.:.:::||:               ..|:::.|.:|::..::|
  Fly   671 LRPGTPYEFKLQSFNSDAASEFSAIRQARTRKTHEQPASSSATPVPANKAVEQHQNSLYPLIAGA 735

  Fly   523 ------ITTASLIIPAVVKLDSGNYTCSPSNSAP---RTIVLHVLNGEYSASAI-------KSGS 571
                  :..|||::...:|        ...||.|   ....|..:..::..||:       |||.
  Fly   736 AGGGILLLIASLVVCLCLK--------RRENSQPEDENKPQLEHIQADFVTSAVLGVGGHHKSGD 792

  Fly   572 V 572
            |
  Fly   793 V 793

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	20/97 (21%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	20/91 (22%)
boi	NP_001096868.3	IG_like	42..131	CDD:214653	3/6 (50%)
		IG_like	154..234	CDD:214653	20/102 (20%)
		Ig	172..234	CDD:299845	17/84 (20%)
		IG_like	249..329	CDD:214653	18/94 (19%)
		Ig	257..329	CDD:299845	18/86 (21%)
		IG_like	339..418	CDD:214653	24/108 (22%)
		Ig	352..408	CDD:299845	18/70 (26%)
		FN3	470..592	CDD:238020	24/155 (15%)
		FN3	613..700	CDD:238020	19/87 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910