DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr15 and Ntm

DIOPT Version :9

Sequence 1:NP_001287299.1 Gene:dpr15 / 41473 FlyBaseID:FBgn0037993 Length:662 Species:Drosophila melanogaster
Sequence 2:NP_001344522.1 Gene:Ntm / 235106 MGIID:2446259 Length:367 Species:Mus musculus


Alignment Length:336 Identity:72/336 - (21%)
Similarity:121/336 - (36%) Gaps:67/336 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   181 PVATTTLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRF 245
            ||.:.....|..:|:   :..:.|..|.|.|.:...|.: ::||..  ..||......:..|.|.
Mouse    30 PVRSGDATFPKAMDN---VTVRQGESATLRCTIDNRVTR-VAWLNR--STILYAGNDKWCLDPRV 88

  Fly   246 QSVFSPNPERWSLQIKYVQLKDEGTYECQVSTE--PKASAIVHLRI-VEPKTELIGESTRHVKAG 307
             .:.|....::|::|:.|.:.|||.|.|.|.|:  ||.|. |||.: |.||...| .|...:..|
Mouse    89 -VLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSR-VHLIVQVSPKIVEI-SSDISINEG 150

  Fly   308 SQVKLRCIISQALEPPLFINW---------FYNQKQIYLHNRRGWRTE----------------I 347
            :.:.|.||.:...||.  :.|         |.::.: ||..:...|.:                :
Mouse   151 NNISLTCIATGRPEPT--VTWRHISPKAVGFVSEDE-YLEIQGITREQSGEYECSASNDVAAPVV 212

  Fly   348 ERIDLPAEVPTTSTTTTTTTTTASTTTTTTSTTPATPSTTATGSTEGATSSETLNGLVTITRSYI 412
            .|:.:....|...:....|........|......|.||.......:.....|...|:....|.::
Mouse   213 RRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLVEGKKGVKVENRPFL 277

  Fly   413 ---------------LDAISQNDVSELGAAAGVAVATETSTAQLLTEVEATSST----------- 451
                           ...::.|.:....|:..:....|.:::.||.||:.|:.|           
Mouse   278 SKLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTLLQEVKTTALTPWKGPGAVSEV 342

  Fly   452 -SGTSTGAGLL 461
             :|||..||.:
Mouse   343 NNGTSRRAGCI 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr15NP_001287299.1 IG_like 197..289 CDD:214653 28/93 (30%)
V-set 204..290 CDD:284989 28/88 (32%)
NtmNP_001344522.1 Ig 44..132 CDD:416386 28/95 (29%)
Ig strand A' 44..49 CDD:409353 0/7 (0%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 0/3 (0%)
FR2 64..70 CDD:409353 1/6 (17%)
Ig strand C 64..70 CDD:409353 1/6 (17%)
CDR2 71..83 CDD:409353 2/13 (15%)
Ig strand C' 72..76 CDD:409353 1/3 (33%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 11/34 (32%)
Ig strand D 87..94 CDD:409353 2/7 (29%)
Ig strand E 97..103 CDD:409353 1/5 (20%)
Ig strand F 110..118 CDD:409353 4/7 (57%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 6/9 (67%)
FR4 125..132 CDD:409353 4/7 (57%)
Ig_3 136..205 CDD:404760 15/72 (21%)
Ig strand A' 144..148 CDD:409353 0/3 (0%)
Ig strand B 151..160 CDD:409353 3/8 (38%)
Ig strand F 197..205 CDD:409353 0/7 (0%)
Ig_3 222..299 CDD:404760 9/76 (12%)
putative Ig strand A 223..229 CDD:409353 0/5 (0%)
Ig strand B 239..243 CDD:409353 1/3 (33%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 0/3 (0%)
Ig strand F 292..297 CDD:409353 0/4 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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