DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr15 and Iglon5

DIOPT Version :9

Sequence 1:NP_001287299.1 Gene:dpr15 / 41473 FlyBaseID:FBgn0037993 Length:662 Species:Drosophila melanogaster
Sequence 2:NP_001157990.1 Gene:Iglon5 / 210094 MGIID:2686277 Length:336 Species:Mus musculus


Alignment Length:308 Identity:75/308 - (24%)
Similarity:126/308 - (40%) Gaps:50/308 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   180 RPVATTTLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQR 244
            |.:.:.:|:.....|:| |:..  |.:|.|.|.:.:.|.: ::||..  .:||......:.:|.|
Mouse    26 RGLLSQSLEFSSPADNY-TVCE--GDNATLSCFIDEHVTR-VAWLNR--SNILYAGNDRWTSDPR 84

  Fly   245 FQSVFSPNPERWSLQIKYVQLKDEGTYECQVST--EP---KASAIVHL--RIVEPKTELIGESTR 302
            .:.:.: .||.:|:.|..|.|.|||.|.|...|  :|   :...|||:  |||...:.:.     
Mouse    85 VRLLIN-TPEEFSILITQVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVA----- 143

  Fly   303 HVKAGSQVKLRCIISQALEPPLFINWFYNQKQIYLHNRRGWRTEIERIDLP----AEVPTTSTTT 363
             |..|..|.|.|:.....||.  :.|    :|:    |.|:.:|.|.:::.    .:.......|
Mouse   144 -VNEGGNVNLLCLAVGRPEPT--VTW----RQL----RDGFTSEGEILEISDIQRGQAGEYECVT 197

  Fly   364 TTTTTTASTTTTTTSTTPATPSTTATGSTEGATSSETLNGLVTITRSYILDAISQND-------- 420
            .....:|..:.....|....|:.|      ..||:.|..|...:.|...: |:...|        
Mouse   198 HNGVNSAPDSRRVLVTVNYPPTIT------DVTSARTALGRAALLRCEAM-AVPPADFQWYKDDR 255

  Fly   421 VSELGAAAGVAVATETSTAQLL-TEVEATSSTSGTSTGAGLLASTSAA 467
            :...|:|.|:.|.||.:.:.|| ..|.|....:.|...|..|.::||:
Mouse   256 LLSSGSAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSAS 303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr15NP_001287299.1 IG_like 197..289 CDD:214653 28/98 (29%)
V-set 204..290 CDD:284989 28/92 (30%)
Iglon5NP_001157990.1 Ig 41..129 CDD:416386 26/94 (28%)
Ig strand A' 41..46 CDD:409353 2/5 (40%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 0/3 (0%)
FR2 61..68 CDD:409353 2/7 (29%)
Ig strand C 61..67 CDD:409353 1/6 (17%)
CDR2 69..79 CDD:409353 2/9 (22%)
Ig strand C' 71..74 CDD:409353 2/2 (100%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 13/35 (37%)
Ig strand D 84..91 CDD:409353 1/7 (14%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 4/7 (57%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 1/8 (13%)
FR4 122..129 CDD:409353 0/6 (0%)
Ig strand A 132..137 CDD:409353 2/4 (50%)
Ig_3 134..199 CDD:404760 17/80 (21%)
Ig strand A' 140..145 CDD:409353 0/10 (0%)
Ig strand B 148..157 CDD:409353 3/8 (38%)
Ig strand C 163..167 CDD:409353 1/9 (11%)
Ig strand D 174..177 CDD:409353 0/2 (0%)
Ig strand E 178..183 CDD:409353 1/4 (25%)
Ig strand F 191..199 CDD:409353 1/7 (14%)
Ig_3 217..295 CDD:404760 20/84 (24%)
putative Ig strand A 218..224 CDD:409353 2/11 (18%)
Ig strand B 234..238 CDD:409353 0/3 (0%)
Ig strand C 247..251 CDD:409353 1/3 (33%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 1/4 (25%)
Ig strand G 301..304 CDD:409353 2/3 (67%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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