DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and Ptprf

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_006502927.1	Gene:	Ptprf / 19268	MGIID:	102695	Length:	1924	Species:	Mus musculus

Alignment Length:	383	Identity:	89/383 - (23%)
Similarity:	140/383 - (36%)	Gaps:	81/383 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 PTID-DYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRFQSVFS-PNP 253
            |||| ..|..:.:.|..|.:.|.........|||.:    ..|.||...  ::.|.:.:.| .:|
Mouse   135 PTIDMGPQLKVVEKGRTATMLCAAGGNPDPEISWFK----DFLPVDPAA--SNGRIKQLRSGGSP 193

  Fly   254 ERWSLQIKYVQLKDEGTYEC----QVSTEPKASAIVHLRI--VEPKTELIGESTRHVKAGSQVKL 312
            .|.:|||:..:..|:|.|||    ...|...|.|.:::|:  |.|:.. |..|::.|..|..|.|
Mouse   194 IRGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFS-IPPSSQEVMPGGSVNL 257

  Fly   313 RCIISQALEPPLFINWFYNQKQIYLHNRRG-WRTEIE-------------------RIDLPAEV- 356
            .|:...|  |..::.|....:::...:... .|..:|                   .|:..|:|
Mouse   258 TCVAVGA--PMPYVKWMMGAEELTKEDEMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVT 320

  Fly   357 -------PTTSTTTTTTTTTASTTTTTTSTTPAT---PSTTATGSTEG--------ATSSETLNG 403
                   |.....|.||.|:.:.|..:.:|.|.:   ....|.| |:|        |::..::.|
Mouse   321 VKALPKPPIDLVVTETTATSVTLTWDSGNTEPVSFYGIQYRAAG-TDGPFQEVDGVASTRYSIGG 384

  Fly   404 LVTITRSYILDAISQNDVSELGAAAGVAVATETSTAQLLTEVEATSSTSGTSTGAGLLASTSAAY 468
            |...: .|....::.|.:       |....:|...|:  |..:|.||.........|.|||....
Mouse   385 LSPFS-EYAFRVLAVNSI-------GRGPPSEAVRAR--TGEQAPSSPPRRVQARMLSASTMLVQ 439

  Fly   469 ------AAGAAAGITTAATGDSAATAATTSAW-LTTMDAEAATTAATTTTTMLPSSSF 519
                  ..|...|.....|.||   ....||| ....||...||..    ::||..::
Mouse   440 WEPPEEPNGLVRGYRVYYTPDS---RRPLSAWHKHNTDAGLLTTVG----SLLPGITY 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	25/96 (26%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	25/92 (27%)
Ptprf	XP_006502927.1	I-set	33..124	CDD:369462
		Ig2_RPTP_IIa_LAR_like	152..232	CDD:319301	23/85 (27%)
		Ig3_RPTP_IIa_LAR_like	252..320	CDD:143216	11/69 (16%)
		FN3	325..414	CDD:238020	20/99 (20%)
		FN3	421..513	CDD:238020	19/77 (25%)
		FN3	518..607	CDD:238020
		FN3	615..709	CDD:238020
		FN3	716..822	CDD:238020
		FN3	827..916	CDD:238020
		FN3	925..1013	CDD:238020
		FN3	1022..>1081	CDD:238020
		PTP_DSP_cys	1352..1627	CDD:391942
		R-PTP-F-2	1629..1919	CDD:350477
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910