DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr15 and Cntn3

DIOPT Version :9

Sequence 1:NP_001287299.1 Gene:dpr15 / 41473 FlyBaseID:FBgn0037993 Length:662 Species:Drosophila melanogaster
Sequence 2:NP_032805.2 Gene:Cntn3 / 18488 MGIID:99534 Length:1028 Species:Mus musculus


Alignment Length:591 Identity:111/591 - (18%)
Similarity:180/591 - (30%) Gaps:198/591 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    97 NGDQRLRLTAALEANLIMSNRNVQEQHSYRITQDNATSAA---SIAPN--GTAFGDAPSIPIGVA 156
            |||.           |::..|...|..:..||..|.|.:.   .||.|  |..:..|....:..|
Mouse   354 NGDA-----------LVLEERIQIENGALTITNLNVTDSGMFQCIAENKHGLIYSSAELKVVASA 407

  Fly   157 PATTTTIDPATTTPTTTTRRTTRRPVATTTLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPI 221
            |                  ..:|.|:.             :.:..|.|:...|.|..:...:...
Mouse   408 P------------------DFSRNPMK-------------KMVQVQVGSLVILDCKPRASPRALS 441

  Fly   222 SWLRMRDGHILTVDQ--TTFIADQRFQSVFSPNPERWSLQIKYVQLKDEGTYECQVSTE-PKASA 283
            .|   :.|.::..:|  .:|:.|             ..|:|..|...|.|||.|....: .||:.
Mouse   442 FW---KKGDMMVREQARVSFLND-------------GGLKIMNVTKADAGTYTCTAENQFGKANG 490

  Fly   284 IVHLRIVEPKTELIGESTRHVKAGSQVKLRCIISQALEPPL---FINWFYNQ------------- 332
            ..||.:.||...::..|...|..|..|.|.|   |....||   ...|::|.             
Mouse   491 TTHLVVTEPTRIILAPSNMDVAVGESVILPC---QVQHDPLLDIMFAWYFNGALTDFKKDGSHFE 552

  Fly   333 ------------KQIYLHNRRGW----RTEIERIDLPAEV--------PTTSTTTTTTTTTA--S 371
                        :.|.|.:...:    :|.::.:...||:        |........|.|||  |
Mouse   553 KVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAAELIVRGSPGPPENVKVDEITDTTAQLS 617

  Fly   372 TTTTTTSTTPA--------TPSTTA-----------TGSTEGATSSETLNGLVTITRSYILDAIS 417
            .|..|.|.:|.        ||.:..           .|.|..||..| ||..|    .|....::
Mouse   618 WTEGTDSHSPVISYAVQARTPFSVGWQSVRTVPEVIDGKTHTATVVE-LNPWV----EYEFRIVA 677

  Fly   418 QNDVSELGAAAGVAVATETSTAQLLTEVEATSSTSGTSTGAGLLASTSAA------------YAA 470
            .|   ::|.......:.:..|.:...|:..:..:.|..:.:.|:.:....            ..|
Mouse   678 SN---KIGGGEPSLPSEKVRTEEAAPEIAPSEVSGGGGSRSELVITWDPVPEELQNGGGFGYVVA 739

  Fly   471 GAAAGITTAATGDSAATAATTSAWLTTMDAEAATTAATTTTTMLPSSSFIKQITTASLIIPAVVK 535
            ....|:||               |:.|:     .|:......:..:.|.:.       ..|..||
Mouse   740 FRPLGVTT---------------WIQTV-----VTSPDNPRYVFRNESIVP-------FSPYEVK 777

  Fly   536 L----DSGNYTCSP------SNSAPRTIVLHVLNGEYSASAIKSGSVSWSALIG--CHGYL---- 584
            :    :.|....||      :...|.....|:.....|:|.|:   |||:.:..  .:|:|    
Mouse   778 VGVYNNKGEGPFSPVTTVFSAEEEPTVAPSHISAHSLSSSEIE---VSWNTIPWKLSNGHLLGYE 839

  Fly   585 --HWRN 588
              :|.|
Mouse   840 VRYWNN 845

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr15NP_001287299.1 IG_like 197..289 CDD:214653 21/94 (22%)
V-set 204..290 CDD:284989 20/88 (23%)
Cntn3NP_032805.2 Ig 25..120 CDD:416386
Ig strand A 27..31 CDD:409353
Ig strand A' 34..39 CDD:409353
Ig strand B 45..53 CDD:409353
Ig strand C 58..64 CDD:409353
Ig strand C' 66..69 CDD:409353
Ig strand D 76..80 CDD:409353
Ig strand E 82..88 CDD:409353
Ig strand F 95..104 CDD:409353
Ig strand G 107..120 CDD:409353
Ig 129..214 CDD:416386
Ig strand A 130..135 CDD:409353
Ig strand B 139..145 CDD:409353
Ig strand C 153..159 CDD:409353
Ig strand C' 164..166 CDD:409353
Ig strand D 171..176 CDD:409353
Ig strand E 179..183 CDD:409353
Ig strand F 193..201 CDD:409353
Ig strand G 203..214 CDD:409353
Ig 227..315 CDD:416386
Ig strand A 227..232 CDD:409353
Ig strand A' 235..240 CDD:409353
Ig strand B 243..252 CDD:409353
Ig strand C 258..262 CDD:409353
Ig strand C' 265..267 CDD:409353
Ig strand D 276..279 CDD:409353
Ig strand E 280..285 CDD:409353
Ig strand F 293..301 CDD:409353
Ig strand G 304..315 CDD:409353
Ig 320..403 CDD:416386 15/59 (25%)
Ig strand A' 326..330 CDD:409353
Ig strand B 334..342 CDD:409353
Ig strand C 348..353 CDD:409353
Ig strand C' 355..358 CDD:409353 2/13 (15%)
Ig strand D 363..367 CDD:409353 1/3 (33%)
Ig strand E 369..374 CDD:409353 0/4 (0%)
Ig strand F 383..390 CDD:409353 2/6 (33%)
Ig strand G 394..403 CDD:409353 1/8 (13%)
Ig 408..496 CDD:416386 24/134 (18%)
Ig strand A 408..413 CDD:409353 1/22 (5%)
Ig strand A' 416..421 CDD:409353 0/17 (0%)
Ig strand B 425..432 CDD:409353 1/6 (17%)
Ig strand C 440..444 CDD:409353 1/6 (17%)
Ig strand D 458..461 CDD:409353 1/2 (50%)
Ig strand E 462..467 CDD:409353 1/4 (25%)
Ig strand F 475..483 CDD:409353 4/7 (57%)
Ig strand G 489..496 CDD:409353 2/6 (33%)
Ig 498..598 CDD:416386 18/102 (18%)
Ig strand A 498..504 CDD:409353 2/5 (40%)
Ig strand A' 507..512 CDD:409353 1/4 (25%)
Ig strand B 515..523 CDD:409353 3/10 (30%)
Ig strand C 532..536 CDD:409353 0/3 (0%)
Ig strand E 560..564 CDD:409353 0/3 (0%)
Ig strand F 573..580 CDD:409353 0/6 (0%)
Ig strand G 587..591 CDD:409353 0/3 (0%)
FN3 598..695 CDD:238020 23/104 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 684..714 3/29 (10%)
FN3 703..795 CDD:238020 16/118 (14%)
FN3 805..898 CDD:238020 11/44 (25%)
FN3 906..991 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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