DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and L1cam

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_032504.3	Gene:	L1cam / 16728	MGIID:	96721	Length:	1259	Species:	Mus musculus

Alignment Length:	304	Identity:	71/304 - (23%)
Similarity:	110/304 - (36%)	Gaps:	74/304 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 NSNGTNGRAFQRTQSRREALIPATTQMAQTLDKASAFRPTMAAALDAAAPNRSSNNVA--INNIS 95
            ||.|:...|:..|.   || .|...|..|    :..:.|...|.||.....|....:.  ||.:|
Mouse   315 NSLGSARHAYYVTV---EA-APYWLQKPQ----SHLYGPGETARLDCQVQGRPQPEITWRINGMS 371

  Fly    96 N---NGDQRLRLTAALEANLIMSNRNVQEQHSYRITQDNATSAASIAPNGTAFGDAPSIPIGVAP 157
            .   |.||:.|:.   :.:||:|  |||...: .:||..|.:     .:|....:| .|.:...|
Mouse   372 METVNKDQKYRIE---QGSLILS--NVQPSDT-MVTQCEARN-----QHGLLLANA-YIYVVQLP 424

  Fly   158 ATTTTIDPATTTPTTTTRRTTRRPVATTTLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPIS 222
            |...|                               .|.||.::..|:.|||.|.........:.
Mouse   425 ARILT-------------------------------KDNQTYMAVEGSTAYLLCKAFGAPVPSVQ 458

  Fly   223 WLRMRDGHILTVDQTTFIADQRFQSVFSPNPERWSLQIKYVQLKDEGTYECQVSTEP-KASAIVH 286
            |        |..:.||.:.|:||...     ...:|.|:.:|..|.|.|.||.:.:. ..:.:.:
Mouse   459 W--------LDEEGTTVLQDERFFPY-----ANGTLSIRDLQANDTGRYFCQAANDQNNVTILAN 510

  Fly   287 LRIVEPKTELIGESTRHVKAGSQVKLRCIISQALEPPL--FINW 328
            |::.|......|..:...|.|::|...|  ..:.:|.|  .|.|
Mouse   511 LQVKEATQITQGPRSAIEKKGARVTFTC--QASFDPSLQASITW 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	23/92 (25%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	21/86 (24%)
L1cam	NP_032504.3	Ig_L1-CAM_like	53..130	CDD:319299
		Ig	133..227	CDD:386229
		Ig3_L1-CAM	259..329	CDD:143284	5/16 (31%)
		Ig	346..421	CDD:386229	23/86 (27%)
		IG_like	433..513	CDD:214653	23/92 (25%)
		Ig	518..607	CDD:386229	9/37 (24%)
		Cell attachment site. /evidence=ECO:0000255	553..555		71/304 (23%)
		Cell attachment site. /evidence=ECO:0000255	562..564
		FN3	611..708	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	697..724
		fn3	717..798	CDD:365830
		fn3	824..904	CDD:365830
		fn3	920..1002	CDD:365830
		Bravo_FIGEY	1146..1231	CDD:372781
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1182..1209
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1228..1259
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910