DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and AgaP_AGAP006083

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_316139.4	Gene:	AgaP_AGAP006083 / 1276754	VectorBaseID:	AGAP006083	Length:	1502	Species:	Anopheles gambiae

Alignment Length:	338	Identity:	69/338 - (20%)
Similarity:	116/338 - (34%)	Gaps:	90/338 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 IPIG------VAPATTTTIDPATTTPTTTTRRTTR---------------RPVATTTLKPPPTID 194
            :|.|      |.||...|.. ...|..|.:|.:::               .|.|...:..|.|:.
Mosquito   166 LPSGALEIDEVVPADRGTYQ-CNVTAGTFSRLSSKSNLNIKSTAGQPQSFAPPAFVIVPQPQTVR 229

  Fly   195 DYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRFQSVFSPNPERWSLQ 259
            :..|:|        |.|......|..|.||  |:|..:.::.    .|.||:.:.:     .|||
Mosquito   230 EGDTVI--------LDCAANGNPKPTIRWL--RNGEDIDMND----LDSRFRIMGT-----GSLQ 275

  Fly   260 IKYVQLKDEGTYECQVS-TEPKASAIVHLRIVEPKTELIGESTRHVKAGSQVKLRCIISQALEPP 323
            |..:|..|.|.|:|:.| ||....|...:::..|...::....:......:::|.|.|..  :|.
Mosquito   276 INSIQDTDAGDYQCRASNTEDSLDASATVQVQVPPKFILSPDDKVAYEKEELELTCSIHG--KPT 338

  Fly   324 LFINWFYNQKQI----YL-----HNRR--------------------GWRTEIERIDL--PAEVP 357
            ..|.|..|...|    |:     ||.:                    |......|:::  |....
Mosquito   339 PIIQWLKNGDLITPSEYMQIVGGHNLKIFGLIGSDAGMFQCIGTNPAGSVQAAARLEIIEPGVTR 403

  Fly   358 TTSTTTTTTTTTASTTT------------TTTSTTPATPSTTATGSTEGATSSETLNGLVTITRS 410
            |...:..:.|....||:            .|.|.|.:...:.....::...|...|:.||:.|::
Mosquito   404 TQYHSDKSGTLRLQTTSGLPKRHKGKKFQQTQSKTKSYEKSPLLLQSDPKLSKSVLDSLVSRTKA 468

  Fly   411 ---YILDAISQND 420
               |..|..:.:|
Mosquito   469 RPKYTNDDYADHD 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	26/92 (28%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	24/86 (28%)
AgaP_AGAP006083	XP_316139.4	Ig	8..107	CDD:299845
		IG_like	12..95	CDD:214653
		IG_like	117..189	CDD:214653	6/23 (26%)
		Ig	<149..204	CDD:299845	9/38 (24%)
		I-set	217..306	CDD:254352	29/107 (27%)
		IGc2	230..293	CDD:197706	22/81 (27%)
		I-set	310..396	CDD:254352	13/87 (15%)
		Ig	331..396	CDD:299845	12/66 (18%)
		FN3	576..668	CDD:238020
		FN3	676..765	CDD:238020
		FN3	772..863	CDD:238020
		FN3	874..955	CDD:238020
		FN3	977..1063	CDD:238020
		FN3	1074..1169	CDD:238020
		Neogenin_C	1236..1497	CDD:284094
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910