DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr15 and AgaP_AGAP008655

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_314755.4	Gene:	AgaP_AGAP008655 / 1275506	VectorBaseID:	AGAP008655	Length:	408	Species:	Anopheles gambiae

Alignment Length:	389	Identity:	73/389 - (18%)
Similarity:	119/389 - (30%)	Gaps:	101/389 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 PATTTPTTTTRRTTRRPVATTTLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDG 229
            |....|......|..|.|:.|.:  ...:..|:|:.:  .||.|          ..::|::....
Mosquito    16 PEFLAPLDNLTVTQGRDVSFTCV--VNNLGQYRTLTT--STHVY----------PQVAWIKSDSK 66

  Fly   230 HILTVDQTTFIADQRFQSVFSPNPERWSLQIKYVQLKDEGTYECQVSTEPKASAIVHLRIVEPKT 294
            .||.: .|..:|.....||.......|.|.|.:|||.|.|:|.|||:|:|....:..|...|.||
Mosquito    67 AILAI-HTHMVALNPRLSVTHNGHNTWKLHISHVQLNDSGSYMCQVNTDPMRHQVSALNESEGKT 130

  Fly   295 ELIGESTRHVKAGSQVKLRCIISQALEPPLFINWFYNQKQIYLHNRRGWRTEIERIDLPAEVPTT 359
                .:...:.||...|::|:                  ::..|.:.....:..|        ..
Mosquito   131 ----STASSLSAGLVCKIQCL------------------KMCTHKKNNPHHQSPR--------PN 165

  Fly   360 STTTTTTTTTASTTTTTTSTTPATPSTTATGSTEGATSSETLNGLVTITRSYILDAISQNDVSEL 424
            |......:...|......:...|.||....|..:...:...:..:     .|.|..|::.:..|.
Mosquito   166 SGQRFNVSRNESVLGCCFAFLSAFPSHQPNGPAQHEATRTPVYAV-----PYALSCINEPNTLEG 225

  Fly   425 GAAAGVAVATETSTAQLLTEVEATSSTSGTSTGAGLLASTSAAYAAGAAAGITTAATGDSAATAA 489
            |      ||.|....||:.:                            |.|:...|.
Mosquito   226 G------VANEGGNVQLVCQ----------------------------ATGVPEPAV-------- 248

  Fly   490 TTSAWLTTMDAEAATTAATTTTTMLPSSSFIKQITTASLIIPAVVKLDSGNYTCSPSNSAPRTI 553
               .|......:      ....|.......:|.:....|::..|.:.|.|.|.|..||..|.::
Mosquito   249 ---QWRRENGKD------IVVRTEGREKQVVKFVEGERLVLNQVQRTDMGGYLCIASNGVPPSV 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	26/91 (29%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	25/85 (29%)
AgaP_AGAP008655	XP_314755.4	I-set	16..134	CDD:254352	36/136 (26%)
		Ig	25..111	CDD:299845	26/100 (26%)
		IG_like	227..311	CDD:214653	20/122 (16%)
		IGc2	230..299	CDD:197706	17/113 (15%)
		Ig	314..408	CDD:299845
		IG_like	332..408	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810