DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and AgaP_AGAP005219

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_314120.4	Gene:	AgaP_AGAP005219 / 1274926	VectorBaseID:	AGAP005219	Length:	1847	Species:	Anopheles gambiae

Alignment Length:	396	Identity:	80/396 - (20%)
Similarity:	125/396 - (31%)	Gaps:	110/396 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 TTPTTTTRRTTRRPVATT------TLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLRM 226
            |..|.|..|.|...:..|      .:.|..:......:.:..|....|||||:.......||.|:
Mosquito   221 TVDTLTGERKTSEAILLTLKDNIPNMAPSTSQKSVSELKAGKGASVQLPCNVQGNPVPSFSWFRI 285

  Fly   227 RD-GHILTVDQTTFIADQRFQSVFSPNPERWSLQIKYVQLKDEGTYECQVST---EPKASAIVHL 287
            .| |.:.||..:..|.           |.:..|.|:.|..:|.|.:.|:...   |.|..  :||
Mosquito   286 SDTGSLYTVPSSQRIV-----------PSQSLLFIRNVDERDAGRWICKAFNQFGEQKLE--IHL 337

  Fly   288 RIVEPKTELIGESTRHVKAGSQVKLRCII--SQALEPPLFINWFYNQKQIYLHNRRGWRTEIERI 350
            .|.......|....:.:.:|:...|.|.|  |:..:    |.||:|.::::.:.|
Mosquito   338 TISNELVAHIHPQIQIINSGNSALLNCSIYGSEVNK----IEWFHNGQELFANGR---------- 388

  Fly   351 DLPAEVPTTSTTTTTTTTTASTTTTTTSTTPATPSTTATGSTEGATSSETLNGLVTITRSYILDA 415
                                                    |.....|:.||.          :|.
Mosquito   389 ----------------------------------------SERSLLSANTLK----------IDR 403

  Fly   416 ISQNDVSELGAAAGV---AVATETSTAQLLTEVEATSSTSGTSTGAGLLASTSAAYAAGAAAGIT 477
            :|:.|       .|:   .|:...|:||..:|::...|....|.|     .......|.|...:.
Mosquito   404 VSKKD-------QGIYQCIVSNARSSAQGSSELKLGESPPEISYG-----FVEQNVRASAYISLK 456

  Fly   478 TAATGDSAATAATTSAWLTTMDAEAATTAATTTTTMLPSSSFIKQITTASLIIPAVVKLDSGNYT 542
            .:|.|    :......||  :|.:.....::.....:.....|....|..|.|..|...|.|.||
Mosquito   457 CSAAG----SPPPQFVWL--LDYQPILDVSSLHRYTMDQFLDINSHVTTHLNISHVHSDDGGLYT 515

  Fly   543 CSPSNS 548
            |..|||
Mosquito   516 CVASNS 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	25/95 (26%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	25/89 (28%)
AgaP_AGAP005219	XP_314120.4	Ig	41..>97	CDD:299845
		IGc2	263..329	CDD:197706	21/76 (28%)
		IG_like	349..430	CDD:214653	23/151 (15%)
		IGc2	356..419	CDD:197706	19/133 (14%)
		Ig	453..530	CDD:143165	18/75 (24%)
		IG_like	543..627	CDD:214653
		IGc2	550..616	CDD:197706
		IG_like	643..721	CDD:214653
		Ig	648..718	CDD:143165
		Ig	724..800	CDD:299845
		I-set	778..871	CDD:254352
		Ig	796..878	CDD:299845
		FN3	875..998	CDD:238020
		FN3	1005..1108	CDD:238020
		fn3	1116..1203	CDD:278470
		FN3	1215..1311	CDD:238020
		Ig	1316..1394	CDD:299845
		IG_like	1323..1395	CDD:214653
		FN3	1406..1495	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810