DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and AgaP_AGAP009518

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_310174.4	Gene:	AgaP_AGAP009518 / 1271391	VectorBaseID:	AGAP009518	Length:	464	Species:	Anopheles gambiae

Alignment Length:	281	Identity:	66/281 - (23%)
Similarity:	99/281 - (35%)	Gaps:	61/281 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 SNNGDQRLRLTAALE-------ANLIMSNRNVQEQH----SYRITQDNATSAASIAPNGTAF--- 145
            |.||:|::..:.||:       |:.:..:|.|...|    ..|:...|..:|......|...
Mosquito    14 SINGNQQISKSDALKLTPEEEMAHFVNQSRMVTCSHPDHPEVRLKWRNPKNAIISETKGRVHIED 78

  Fly   146 -GDAPSIPIGVAPAT-----TTTIDPATTTPTTTTRRTTRRPVATTTLK----PPPTIDDYQTI- 199
             ||:.::.......|     |..:|...|...|..|.|.  |....:.|    .|.:..|..|:
Mosquito    79 KGDSLALIFEAIARTDQGNWTCEVDVEGTATATEGRVTV--PALRKSFKMIVYEPISFRDTNTVQ 141

  Fly   200 ISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRFQSVFSPNPERWS-----LQ 259
            .:.....|.:.|.||...:..:||.              |.....|..:|| |..|:|     :.
Mosquito   142 TAVEDKDATIRCEVKGHPEPSVSWY--------------FNGQPLFCKLFS-NNGRYSKLADGMS 191

  Fly   260 IKYVQLKDEGTYECQV--------STEPKASA--IVHLRIVEPKTELIGESTRHVKAGSQVKLRC 314
            ||.|...|.|.|.|:.        |.|.|...  |.|...:.|..:.|.::..:|  |..|.|.|
Mosquito   192 IKKVVQNDSGEYTCKAFQISATGSSFEEKTIRLNIKHKPYMPPWKKSISDAYGYV--GGMVNLTC 254

  Fly   315 IISQALEPPLFINWFYNQKQI 335
              ....|||...:|..|.|::
Mosquito   255 --EATAEPPANFSWSANNKKL 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	26/107 (24%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	25/100 (25%)
AgaP_AGAP009518	XP_310174.4	IG_like	45..117	CDD:214653	14/71 (20%)
		Ig	<67..102	CDD:299845	5/34 (15%)
		IGc2	145..207	CDD:197706	20/76 (26%)
		IG_like	240..320	CDD:214653	11/38 (29%)
		Ig	250..318	CDD:143165	9/26 (35%)
		FN3	325..429	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900