DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and si:dkey-24p1.7

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_005173465.1	Gene:	si:dkey-24p1.7 / 101883966	ZFINID:	ZDB-GENE-121214-215	Length:	598	Species:	Danio rerio

Alignment Length:	501	Identity:	89/501 - (17%)
Similarity:	161/501 - (32%)	Gaps:	157/501 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RLILLALLICLPAIRGQAEETSILNSNGTNGRAFQRTQSRREALIPATTQMAQTLDKASAFRPTM 73
            ::|.|..:|.:.......||      |..||.....:.....|:......::.|.....|..|..
Zfish     2 KIISLCTIIFMLVFNVLCEE------NADNGWNISFSPREVTAVKGLCAHISCTFTYPVAENPIQ 60

  Fly    74 AAALDAAAPNRSSNNVAINNISNNGDQRLRL--TAALEANLIMSNRNV--------QEQHSYRIT 128
            :....:.......|.:..||:..|..::..|  ...||.:|..:|.::        ::::::||.
Zfish    61 SVIWQSCVAKDKCNLIFQNNVEKNKLKKNELGHIKMLEPDLSKNNCSIILKDIKENEKEYTFRIK 125

  Fly   129 QD-----NATSAASIAPNGTAFGDAPSIPIGVAPATTTTID---------PATTTPTTTTRRTTR 179
            ..     |.|...||.       |.|::   |.|..:..::         |...||
Zfish   126 AKQQYTFNPTVKISIK-------DEPTL---VVPPLSEKVEVNLTCSAPFPCPETP--------- 171

  Fly   180 RPVATTTLKPPP----TIDD--------------YQTIISQAGTH-AYLPCNVKQLVKK------ 219
             ||.|..:|...    .:|:              |.|:|..:..| ..:.|:|:...||
Zfish   172 -PVITWWIKTKEENYIKLDNNKITQVHSEHVYYSYLTLIPTSDQHDGTVGCDVRYGNKKINTNNT 235

  Fly   220 -PISWLR---------MRDGHILTVDQTTFIADQRFQS---------VFSPNPER-------WSL 258
             .:.:::         :.:|..|.:..|       |:|         .|:.|.:.       .:|
Zfish   236 LEVKYVQALQIVGENTLMEGDTLNLTCT-------FRSHPPASNPVWRFNGNTDNLNTQTSAGTL 293

  Fly   259 QIKYVQLKDEGTYECQVSTEPKA-SAIVHLRIVEPKTELIGESTRHVKAGSQVKLRCIIS---QA 319
            .|..|..:..|.|.|:::...|. :|.:.:.|.|  ..::||:  .:|.|..:.|.|...   |:
Zfish   294 MIANVGKEHAGIYVCEMTYMNKTLNASITINITE--VNILGEN--RLKKGDTLNLTCSFKNHPQS 354

  Fly   320 LEPPLFINWFYNQKQIYLHNRRGWRTEIERIDLPAEVPTTSTTTTTTTTTASTTTTTTSTTPATP 384
            ...|:   |.:|.....|.|:                             ||........  .|.
Zfish   355 SSNPV---WSFNGDADKLKNQ-----------------------------ASAANLIIDN--VTK 385

  Fly   385 STTATGSTEGATSSETLNGLVTITRSYILDAISQNDVSELGAAAGV 430
            ......:.|.....:|||..:|:.       |:::|:......|||
Zfish   386 EHAGIYACEMTYMKKTLNASITVD-------ITEHDMGRNNTRAGV 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	22/125 (18%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	20/119 (17%)
si:dkey-24p1.7	XP_005173465.1	Ig	27..132	CDD:299845	15/104 (14%)
		IG_like	251..325	CDD:214653	15/80 (19%)
		Ig	254..323	CDD:299845	15/75 (20%)
		ig	336..394	CDD:278476	13/91 (14%)
		IG_like	339..408	CDD:214653	16/102 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000