DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and ntm

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	439	Identity:	96/439 - (21%)
Similarity:	156/439 - (35%)	Gaps:	118/439 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 PVATTTLKPPPTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLRMRDGHILTVDQTTFIADQRF 245
            ||.:.....|..:|:   :..:.|..|.|.|.|...|.: ::||..  ..||......:..|.|.
Frog    31 PVRSGDAGFPKAMDN---VTVRQGDSAILRCTVDNRVTR-VAWLNR--STILYTGNDKWSIDPRV 89

  Fly   246 QSVFSPNPERWSLQIKYVQLKDEGTYECQVSTE--PKASAIVHLRIVEPKTELIGESTRHVKAGS 308
             .:.:....::|::|:.|.:.|||.|.|.|.|:  ||.|. |||.:..|...:...|:..|..||
Frog    90 -VLLANTKSQYSIEIQNVDIYDEGPYTCSVQTDNHPKTSR-VHLIVQVPPRIVDISSSIAVNEGS 152

  Fly   309 QVKLRCIISQALEPPLFINWFYNQKQIYLHNRRGWRTEIERIDLPAEVPTTSTTTTTTTTTASTT 373
            .|.|.||.:...||  .:||.|...:     .||:.:|.|.:::          |..|...:...
Frog   153 NVSLICIANGRPEP--VVNWRYLSPK-----ARGFVSEDEYLEI----------TGITREQSGIY 200

  Fly   374 TTTTSTTPATPSTTATGSTEGATSSETLNGLVTITRS---YILDAISQNDVSELGAAAGVAVATE 435
            ..:.|...:.|....                |.:|.:   |||||  ||    :||..|
Frog   201 ECSASNDVSAPDVRR----------------VKLTVNYPPYILDA--QN----IGAPLG------ 237

  Fly   436 TSTAQLLTEVEATSSTSGTSTGAGLLASTSAAYAAGAAAGITTAATGDSAATAATTSAWLTTMDA 500
                                 ..|:|..                   :::|..|....|.    .
Frog   238 ---------------------HRGILQC-------------------EASAVPAADFFWY----K 258

  Fly   501 EAATTAATTTTTMLPSSSFIKQITTASLIIPAVVKLDSGNYTCSPSN---SAPRTIVLHVLNGEY 562
            |....:.:.....:.:...|.::|..:     |.:.|.|||||...|   .:..:|:|..|....
Frog   259 EDKRLSDSWRGVKVENRETISRVTFLN-----VSEQDYGNYTCMAKNLLGHSNASIILFELFQST 318

  Fly   563 SASAIKSGSVSWSALIGCHGYLHWRN--------VSTLLTLLWIIKFAL 603
            |:..::..|.:....:...|.:|..|        .:.||.||.::.|:|
Frog   319 SSPLLQEESTAALTPLKGPGAVHDGNSGSTQCSFCAPLLILLLLLPFSL 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	28/93 (30%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	28/87 (32%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	28/95 (29%)
		IG_like	45..133	CDD:214653	28/95 (29%)
		IG_like	143..220	CDD:214653	22/109 (20%)
		IGc2	150..209	CDD:197706	18/75 (24%)
		ig	227..311	CDD:278476	25/144 (17%)
		IG_like	230..311	CDD:214653	22/139 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000