DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and myot

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_002664374.4	Gene:	myot / 100329862	ZFINID:	ZDB-GENE-110411-129	Length:	814	Species:	Danio rerio

Alignment Length:	398	Identity:	79/398 - (19%)
Similarity:	136/398 - (34%)	Gaps:	106/398 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 TNGRAFQRTQSRREALIPATTQMAQTLD----KASAFRPTMAAALDAAAPNRSSNNVAINNISNN 97
            |..|:.|.:.      :|..|..:..|.    |.:..||...|..:..   :.|.:..:.::
Zfish   442 TTARSLQSSP------VPHITYTSNMLPKPILKKNVSRPVSRATDEDI---QGSKDALMQDL--- 494

  Fly    98 GDQRLRLTAALEANLIMSNRNVQEQHSY--RITQD--NATSAASIAPNGTAFGDAPSIPIGVAPA 158
             :|:||       |.:...||.|::.||  |:.:.  .|.:|||:.....:|...|:.| |
Zfish   495 -EQKLR-------NKVPQQRNNQQKISYEERMARRLLGADNAASVFHLENSFSSQPAQP-G---- 546

  Fly   159 TTTTIDPATTTP---TTTTRRTTRRPVATTTLK----PPPTIDDYQTIISQAGTHAYLPCNVKQL 216
                 .|....|   .:..:|:.......:|::    .|..|...|.:..:.|....:...|..|
Zfish   547 -----SPEDQYPGGIWSRKKRSGGDSTEASTIQEKCFAPRFIQVPQDVTVEEGRFCRIDFKVVGL 606

  Fly   217 VKKPISW------LRMRDGHILTVDQTTFIADQRFQSVFSPNPERWSLQIKYVQLKDEGTYECQV 275
            ....|||      :|..|.|.:.|.:         :||.       |..|:.|.:...|.|||..
Zfish   607 PTPDISWYLDGKPIRPDDYHKMLVCE---------KSVH-------SFIIEIVTIHHAGLYECIA 655

  Fly   276 STEPKASAI-VHLRIVE-----PKTELIGESTRHVKAGSQVKLRCIISQALEPPLFINWFYNQKQ 334
            ......|.. :||.::.     |.|.::.....|...|..|:|.|.::.:..|.|:  |..:::.
Zfish   656 KNRAGQSQFSLHLDVIAQEQLCPPTFVVKMKNSHAMEGDAVRLECKVNASPSPQLY--WKKDKEM 718

  Fly   335 IYLHNRR-----------------------GWRTEIERIDLPAEVPTTSTTTTTTTTTASTTTTT 376
            :.:.:.|                       ||.|       .:.:.....:|.......:|....
Zfish   719 LRIDHTRMSLSQDSSGKQCLVINPVMKSDAGWYT-------VSAINEAGMSTCNARLDVATRLNK 776

  Fly   377 TSTTPATP 384
            | |.||.|
Zfish   777 T-THPARP 783

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	23/98 (23%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	22/92 (24%)
myot	XP_002664374.4	I-set	68..165	CDD:254352
		Ig	85..161	CDD:143165
		Ig	579..665	CDD:299845	23/101 (23%)
		I-set	580..670	CDD:254352	25/105 (24%)
		I-set	679..770	CDD:254352	14/99 (14%)
		Ig	696..770	CDD:299845	11/82 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910