DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr15 and kirrel1b

DIOPT Version :9

Sequence 1:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_017212964.1	Gene:	kirrel1b / 100170816	ZFINID:	ZDB-GENE-070912-173	Length:	801	Species:	Danio rerio

Alignment Length:	541	Identity:	112/541 - (20%)
Similarity:	181/541 - (33%)	Gaps:	137/541 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 RPVATTTLKPP--PTIDDYQTIISQAGTHAYLPCNVKQLVKKPISWLR-MRDGHIL--TVDQTTF 239
            |....|.|.||  |.|:....|:..|||...|.|..:.  .||:|.:. .:||.|:  ....|..
Zfish   114 RRAKLTVLIPPDGPVIEGSPEILLTAGTSFNLTCVSRG--AKPMSTIEWYKDGIIVEGAHTSTEV 176

  Fly   240 IADQRFQSVFSPNPERWSLQIKYVQLKDEGTYECQVS--TEP--KASAIVHLRIVEPKTELIGES 300
            ::|::..:..|      .|:|:.:.......:.|..|  ..|  |.|.:. |.|..|.|.::...
Zfish   177 LSDRKRVTTKS------FLEIQPMDTDTGRNFTCVASNLAAPLGKRSTVT-LNIHHPPTVILSIE 234

  Fly   301 TRHVKAGSQVKLRCIISQALEPPLFINWFYNQKQIYLHNRR----------GWRTE--------- 346
            .|.|..|.:||..|   ||...|..:.:.:.:..:.|...|          .:.||
Zfish   235 PRSVLEGERVKFTC---QATANPPIMGYRWAKGGVILDGARESVFETTADHSFFTEPVSCLVFNA 296

  Fly   347 --IERIDLPAEV---PTTSTTTTTTTTTASTTTTTTSTTPATPSTTATGSTEGATSSETLNGLVT 406
              ...:.:..:|   |.........|....:..|........|..|.|.:.:|  ||..|:.
Zfish   297 VGSTNVSILVDVHFGPILVVEPRPVTVDVDSDVTLNCKWSGNPPLTLTWTKKG--SSMVLSN--- 356

  Fly   407 ITRSYILDAISQNDVSELGAAA-----GVAVATETSTAQLLTEVEATSSTSGTSTGAGLLASTSA 466
             :....|.::||.|..:....|     ||.            |.|.|.    |..|..:::|...
Zfish   357 -SNQLFLKSVSQADAGQYVCKAIVPRIGVG------------ETEVTL----TVNGPPIISSEPI 404

  Fly   467 AYAAGAAAG-----ITTAATGDSAATAATTSAW----------LTTMDAEAATTAATTTTTMLPS 516
            .||.....|     |.:....|....|...:.|          .|...:..||......:|
Zfish   405 QYAVRGEKGEIKCYIASTPPPDKIVWAWKENVWEKERGTLLERYTVEQSRPATQGGAVLST---- 465

  Fly   517 SSFIKQITTASLIIPAVVKLD-SGNYTCSPSNS-APRTIVLHVLNGEYSA------SAIKSGSVS 573
                       |.|..|::.| ...|.|:..|: .|.|:::.:...:.::      ..|..|||.
Zfish   466 -----------LTINNVMEADFQSTYNCTAWNAFGPGTMIITLEETDIASEDIVPVGVIAGGSVG 519

  Fly   574 WSALIGCHGYLHWRNVSTLLTLLWIIKFALARDICQPNATSKATTRTSLLRAGDGATADVTRETG 638
            .|.|              ||.||:.:.|.|.|        .:.::|..:....|.....|.:||.
Zfish   520 SSIL--------------LLLLLFALIFYLYR--------QRKSSRRGVTLKPDIKVETVNKETN 562

  Fly   639 PKSGASFHRVSSSISATKVAE 659
            .:..|     :|:.:||::.:
Zfish   563 LEEEA-----ASASTATRMVK 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	23/98 (23%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	21/92 (23%)
kirrel1b	XP_017212964.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810