DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr17 and igsf9bb

DIOPT Version :9

Sequence 1:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	308	Identity:	74/308 - (24%)
Similarity:	110/308 - (35%)	Gaps:	114/308 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   415 ITAQMGNHAYMPCQ-IHRLSDKP--VSWVRMRDNHIISVDETTFIADERFQSIYQEDHDYTW--- 473
            :|::.|....:.|. :|.|:.:|  |.|.:..    :.:   .|..:.||...: .|.:|..
Zfish    33 VTSRAGETVILGCDVVHPLNGQPYVVEWFKFG----VPI---PFFINFRFYPPH-VDPEYAGRAS 89

  Fly   474 -----SLQIKYVEPSDAGWYECQ-MATEPKL-----SAKVHLQIVKPKTELIGDQSRFVKA--GS 525
                 ||:|:.|...|.|||||: :..|.:.     .:.|||.:..|.| ......::|:|  |.
Zfish    90 LHGKSSLRIERVRSEDQGWYECKVLMLEQQYHTFHNGSWVHLTVNAPPT-FTDTPPQYVEAKEGG 153

  Fly   526 KVALHCIVRGTLDPPKYIIWFR--------GQKKISD--------SDERTGWYT----------- 563
            .:.|.|...|  :|...:.|.|        .:.|:||        |.|..|.||
Zfish   154 SITLSCTAFG--NPKPSVSWLREGNPVQDSTKYKVSDGSLTLVSISREDRGAYTCRAYSEQGEAV 216

  Fly   564 ----------------------QLDRNIFGTV----------------GDN---QNTI------- 580
                                  .:.::.|.|.                .||   :|.:
Zfish   217 HTTRLLVQGPPFIVSPPENITVNISQDAFFTCQAEAYPGNLTYTWFWEEDNVFFKNDLKRRVSIL 281

  Fly   581 --GSLIIPLVRKEDSGNYTCQPSNSV----SVSVDLHVLSGEYSASAI 622
              |||||..|:.||:|.|||.||||:    |.|..|.|   .|.|..|
Zfish   282 IDGSLIISQVKPEDAGKYTCSPSNSLGRPPSASAYLTV---HYPARVI 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	22/86 (26%)
		Ig	415..507	CDD:299845	27/108 (25%)
		IG_like	521..612	CDD:214653	41/173 (24%)
		IGc2	524..605	CDD:197706	36/161 (22%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653	23/87 (26%)
		Ig	41..113	CDD:143165	21/79 (27%)
		IG_like	144..223	CDD:214653	17/80 (21%)
		IGc2	151..208	CDD:197706	15/58 (26%)
		I-set	227..319	CDD:254352	24/91 (26%)
		Ig	<263..319	CDD:299845	22/55 (40%)
		Ig_2	326..414	CDD:290606	1/1 (100%)
		IG_like	329..403	CDD:214653
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910