DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr17 and negr1

DIOPT Version :9

Sequence 1:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	XP_009300786.1	Gene:	negr1 / 445374	ZFINID:	ZDB-GENE-040822-27	Length:	360	Species:	Danio rerio

Alignment Length:	238	Identity:	60/238 - (25%)
Similarity:	91/238 - (38%)	Gaps:	51/238 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   400 AGSAVRRNLTMPVLNITAQMGNHAYMPCQIHRLSDKPVSWVRMRDNHIISVDETTFIADERFQSI 464
            ||..|  :.|....::.::.|:.|.:.|.:.....|. :|  :..:.||......:..|.|...:
Zfish    34 AGQTV--DYTTSSESVVSRQGDTALLRCYLLDGISKG-AW--LNRSSIIYAGNDKWSGDPRVSIV 93

  Fly   465 YQEDHDYTWSLQIKYVEPSDAGWYECQMATEPKLSAKVHLQIVKPKTELIGDQSRF-VKAGSKVA 528
            ......:.:||||:.|:.:|.|.|.|.:.:|..|..|:...|||...::....|.. |..||.|:
Zfish    94 SNVGDKHEYSLQIQKVDVTDEGVYTCSIQSERNLHPKLIQLIVKVPPKIYDISSDITVNEGSNVS 158

  Fly   529 LHCIVRGTLDPPKYIIWFRGQKKISDSDERTGWYTQLDRNIFGTVGDNQNTIGSLIIPLVRKEDS 593
            |.|...|..:|           |||       |     |:               |.|..||.:|
Zfish   159 LICAASGKPEP-----------KIS-------W-----RH---------------ISPSARKYES 185

  Fly   594 GNYTCQPSNSVSVSVDLHVLSGEYSASAIMSTAARTTKGGRST 636
            |.|.    |...:|.|   .:|:|...|....|:..||..|.|
Zfish   186 GEYL----NITGISRD---QAGDYECGAENDIASPDTKTVRVT 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	17/76 (22%)
		Ig	415..507	CDD:299845	21/91 (23%)
		IG_like	521..612	CDD:214653	23/90 (26%)
		IGc2	524..605	CDD:197706	20/80 (25%)
negr1	XP_009300786.1	Ig	42..121	CDD:299845	18/81 (22%)
		IG_like	44..136	CDD:214653	21/94 (22%)
		I-set	140..222	CDD:254352	32/127 (25%)
		IGc2	153..208	CDD:197706	25/99 (25%)
		IG_like	236..312	CDD:214653
		IGc2	238..304	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810