DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr17 and dpr16

DIOPT Version :9

Sequence 1:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_001287169.1	Gene:	dpr16 / 40619	FlyBaseID:	FBgn0037295	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	502	Identity:	205/502 - (40%)
Similarity:	274/502 - (54%)	Gaps:	81/502 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 PTEATSSW-------SSTAVARGMSSADGAGEAIATSQSAQIGLTTQATVRQTEAQTASTATQAA 253
            |:.:..||       ..|...||.....|:|.:..|: |..:......:.|...|..|:|||...
  Fly     2 PSPSGMSWRQRERGAGGTPGGRGAGILAGSGRSPGTA-SILLAFLAAVSFRGMRAPLAATATPME 65

  Fly   254 AATSAATSAAIASAAAATETAAEMLISTIYPASTETDLHNS-IERVEGQRGKMANAFHPGVPD-- 315
            .|:..|:.|...|...:..:...||.........:|.:.:| .:|                ||
  Fly    66 NASLIASPATGTSTMGSAGSPVLMLGDDQQQQEYDTTVVDSWSDR----------------PDTA 114

  Fly   316 SLTKGFSIPTFLPPFPVFAAADLP--AYRAAADAAEAAKLAAEAAAQAAAAKTSSEAVTMSPEEQ 378
            :||||||||::|||||.|..||||  ...|::.||..|.:....:...:.....|.......|::
  Fly   115 TLTKGFSIPSYLPPFPEFIPADLPHMLRNASSGAAPPADIGPSGSPMPSKPNEQSRLHAYDSEQK 179

  Fly   379 RRQMFNEQHSYLAAHRDGGDGAGSAVRRNLTMPVLNITAQMGNHAYMPCQIHRLSDKPVSWVRMR 443
            .:|:..|:.  ||..|:      ...||.|::|.||.|.|.|.|||:||::::.|.||:||||:|
  Fly   180 AQQLRREKE--LAKERE------LLPRRQLSLPPLNATVQAGQHAYLPCKLNQHSGKPLSWVRLR 236

  Fly   444 DNHIISVDETTFIADERFQSIYQ--------------------------------------EDHD 470
            |.|||:||.||||.|.||.|:.|                                      ....
  Fly   237 DEHIIAVDHTTFINDARFASLLQSTTLTTLVSGGALSTTATPVAALGNSFAHAVPGGQERGNSSS 301

  Fly   471 YTWSLQIKYVEPSDAGWYECQMATEPKLSAKVHLQIVKPKTELIGDQSRFVKAGSKVALHCIVRG 535
            .:|:||||||...||||||||:|||||:||||.|.::.|:||||||:.|||||||:|.|||||||
  Fly   302 LSWTLQIKYVNLEDAGWYECQLATEPKMSAKVQLFVITPRTELIGDRQRFVKAGSRVELHCIVRG 366

  Fly   536 TLDPPKYIIWFRGQKKISDSDE----RTGWYTQLDRNIFGTVGDNQNTIGSLIIPLVRKEDSGNY 596
            ||:.||||.|:||.::::..:|    ::|||||:||||||:...|:||||||:||||||..||||
  Fly   367 TLEAPKYIFWYRGDQQVTAENEASGAQSGWYTQIDRNIFGSTEHNRNTIGSLVIPLVRKIHSGNY 431

  Fly   597 TCQPSNSVSVSVDLHVLSGEYSASAIMSTAARTTK--GGRSTCHSTL 641
            ||:|.||.:.|:.|||||||||||||.|||||..:  .|.::.|..|
  Fly   432 TCEPENSAAASMQLHVLSGEYSASAIKSTAARPHRLGHGYTSLHQWL 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	45/114 (39%)
		Ig	415..507	CDD:299845	56/129 (43%)
		IG_like	521..612	CDD:214653	58/94 (62%)
		IGc2	524..605	CDD:197706	53/84 (63%)
dpr16	NP_001287169.1	IG_like	205..337	CDD:214653	58/131 (44%)
		Ig	<298..338	CDD:299845	25/39 (64%)
		IG_like	352..447	CDD:214653	58/94 (62%)
		Ig	358..439	CDD:143165	50/80 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449717
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1457433at2759
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850