DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr17 and kirrel1a

DIOPT Version :9

Sequence 1:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_001349348.1	Gene:	kirrel1a / 405804	ZFINID:	ZDB-GENE-040426-2126	Length:	819	Species:	Danio rerio

Alignment Length:	245	Identity:	55/245 - (22%)
Similarity:	88/245 - (35%)	Gaps:	74/245 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   438 SWVRMRDNHIISVDETTFIADERFQSIYQEDHDYTWSLQIKYVEPSDAGWYECQMATEPKL-SAK 501
            :|.|.|...::.|.:                    ::|:|...|.||...|||| |||..| |.:
Zfish    67 AWPRYRVLRLVDVGQ--------------------YNLEISAAELSDDSLYECQ-ATEAALRSRR 110

  Fly   502 VHLQIVKPKTELI--GDQSRFVKAGSKVALHCIVRGTLDPPKYIIWFRGQKKISDSDERTGWYTQ 564
            ..|.::.|..|.:  |.....:.||....:.|:.||. .|...|.|.:....|..:...|
Zfish   111 AKLTVLIPPDEPVIEGSPEILLTAGVPYNMSCVSRGA-KPASVIEWQKDGLPIEGAVSTT----- 169

  Fly   565 LDRNIFGTVGDNQNTIGSLIIPLVRKE-DSG-NYTCQPSN-------SVSVSVDLH--------- 611
                  ..:.|.:.......:|:...: |:| |:||..:|       ..::::::|
Zfish   170 ------EVLPDRKRVTTRSYLPIQPLDTDTGKNFTCVATNLAVPMGKRATITLNVHHPPVVTLSI 228

  Fly   612 ----VLSGEYSASAIMSTAARTTKGGRSTCHSTLGLLGILGLLWAMQGAM 657
                ||.||           |.|    .||.:|.. ..|:|..||..|.:
Zfish   229 EPRSVLEGE-----------RVT----FTCQATAN-PPIMGYKWAKGGVV 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	11/52 (21%)
		Ig	415..507	CDD:299845	19/69 (28%)
		IG_like	521..612	CDD:214653	19/112 (17%)
		IGc2	524..605	CDD:197706	17/89 (19%)
kirrel1a	NP_001349348.1	I-set	21..115	CDD:333254	19/68 (28%)
		Ig2_KIRREL3-like	137..218	CDD:143236	16/92 (17%)
		I-set	222..303	CDD:333254	14/57 (25%)
		Ig_3	307..372	CDD:316449
		Ig5_KIRREL3	390..493	CDD:143306
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910