Protein Alignment dpr17 and LSAMP

DIOPT Version :10

• Sequence 1: NP_731670.1
• Gene: dpr17 / 41470
• FlyBaseID: FBgn0051361
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: NP_001305844.1
• Gene: LSAMP / 4045
• HGNCID: 6705
• Length: 361
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 78/330 - (23%)
• Similarity: 123/330 - (37%)
• Gaps: 101/330 - (30%)

  Fly   414 NITAQMGNHAYMPCQIHRLSDKPVSWVRMRDNHIISVDETTFIADERFQSIYQEDHDYTWSLQIK 478
            |||.:.|:.|.:.|.:...:.| |:|  :..:.||......:..|.|.:  .::.|...:||:|:
Human    40 NITVRQGDTAILRCVVEDKNSK-VAW--LNRSGIIFAGHDKWSLDPRVE--LEKRHSLEYSLRIQ 99

  Fly   479 YVEPSDAGWYECQMAT--EPKLSAKVHLQI-VKPKTELIGDQSRFVKAGSKVALHCIVRGTLDPP 540
            .|:..|.|.|.|.:.|  |||.| :|:|.: |.||...|..... |..||.|.|.|:..|..:|
Human   100 KVDVYDEGSYTCSVQTQHEPKTS-QVYLIVQVPPKISNISSDVT-VNEGSNVTLVCMANGRPEP- 161

  Fly   541 KYIIW---------FRGQK----------------------KISDSDER---------------- 558
             .|.|         |.|::                      ::|.:|.:
Human   162 -VITWRHLTPTGREFEGEEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESK 225

  Fly   559 -----TG------------------WYTQLDRNIFGTVG-DNQNTIG--SLIIPLVRKEDSGNYT 597
                 ||                  ||.. |..|....| :.::|.|  ||.:..|.:|..||||
Human   226 SNEATTGRQASLKCEASAVPAPDFEWYRD-DTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYT 289

  Fly   598 CQPSNSVSVSVDLHVLSGEYSASAIMSTAARTTKGGRSTCH-------STLGLLGILGL---LWA 652
            |..:|.:.|:....||     ...::.|.....:...:|.|       |..|:.|.:.|   ||.
Human   290 CVAANKLGVTNASLVL-----FKRVLPTIPHPIQEIGTTVHFKQKGPGSVRGINGSISLAVPLWL 349

  Fly   653 MQGAM 657
            :..::
Human   350 LAASL 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_731670.1	V-set	415..507	CDD:462230	28/94 (30%)
		IG_like	521..612	CDD:214653	34/163 (21%)
		Ig strand B	527..531	CDD:409353	2/3 (67%)
		Ig strand C	542..546	CDD:409353	2/12 (17%)
		Ig strand E	581..585	CDD:409353	3/5 (60%)
		Ig strand F	595..600	CDD:409353	4/4 (100%)
LSAMP	NP_001305844.1	Ig	38..128	CDD:472250	29/93 (31%)
		Ig strand B	49..53	CDD:409353	1/3 (33%)
		Ig strand C	61..65	CDD:409353	3/6 (50%)
		Ig strand E	94..98	CDD:409353	2/3 (67%)
		Ig strand F	108..113	CDD:409353	2/4 (50%)
		Ig strand G	121..124	CDD:409353	1/3 (33%)
		Ig_3	131..201	CDD:464046	15/72 (21%)
		Ig_3	218..294	CDD:464046	18/76 (24%)