Protein Alignment dpr17 and IGLON5

DIOPT Version :10

• Sequence 1: NP_731670.1
• Gene: dpr17 / 41470
• FlyBaseID: FBgn0051361
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: NP_001094842.1
• Gene: IGLON5 / 402665
• HGNCID: 34550
• Length: 336
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 59/257 - (22%)
• Similarity: 90/257 - (35%)
• Gaps: 72/257 - (28%)

  Fly   407 NLTMPVLNITAQMGNHAYMPCQIHRLSDKPVSWVRMRDNHIISVDETTFIADERFQSIYQEDHDY 471
            |::.||   |...|.:..:.|......:..|:|.::||.         |.::...
Human   137 NISSPV---TVNEGGNVNLLCLAVGRPEPTVTWRQLRDG---------FTSEGEI---------- 179

  Fly   472 TWSLQIKYVEPSDAGWYEC----QMATEPKLSAKVHLQIVKPKTELIGD-QSRFVKAGSKVALHC 531
               |:|..::...||.|||    .:.:.|. |.:|.:.:..|.|  |.| .|.....|....|.|
Human   180 ---LEISDIQRGQAGEYECVTHNGVNSAPD-SRRVLVTVNYPPT--ITDVTSARTALGRAALLRC 238

  Fly   532 IVRGTLDPPKYIIWFRGQKKISDSDERTGWYTQLDRNIFGTVGDNQNTIGSLIIPLVRKEDSGNY 596
            .....  ||....|::..:.:| |....|...|.:|           |...|:...|.....|||
Human   239 EAMAV--PPADFQWYKDDRLLS-SGTAEGLKVQTER-----------TRSMLLFANVSARHYGNY 289

  Fly   597 TCQPSNSVSVSVDLHVLSGEYSAS-------AIMSTAARTTKGGRSTCHSTLGLLGILGLLW 651
            ||:.:|.:..|          |||       ::.::|.|..        ..|.||..||.||
Human   290 TCRAANRLGAS----------SASMRLLRPGSLENSAPRPP--------GLLALLSALGWLW 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_731670.1	V-set	415..507	CDD:462230	18/95 (19%)
		IG_like	521..612	CDD:214653	21/90 (23%)
		Ig strand B	527..531	CDD:409353	1/3 (33%)
		Ig strand C	542..546	CDD:409353	0/3 (0%)
		Ig strand E	581..585	CDD:409353	1/3 (33%)
		Ig strand F	595..600	CDD:409353	4/4 (100%)
IGLON5	NP_001094842.1	Ig strand G	122..125	CDD:409382
		Ig_3	134..199	CDD:464046	18/86 (21%)
		Ig_3	217..295	CDD:464046	24/93 (26%)
		Ig	41..129	CDD:472250
		Ig strand B	50..54	CDD:409382
		Ig strand C	62..66	CDD:409382
		Ig strand E	95..99	CDD:409382
		Ig strand F	109..114	CDD:409382