DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr17 and DIP-theta

DIOPT Version :9

Sequence 1:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster

Alignment Length:	313	Identity:	68/313 - (21%)
Similarity:	118/313 - (37%)	Gaps:	77/313 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   343 AAADAAEAAKLAAEAAAQAAAAKTSSEAVTMSPEEQ---RRQMF----NEQHSYLAAH---RDGG 397
            |.|.||..:.:....|....||:.|.:...:...:|   :.|.|    :|:|.::|.|   ....
  Fly    44 ATATAAVVSIICLSLALPGCAAQESDDEGELHHLDQMHHQHQDFIIGESEEHDHIAHHLAEMQNK 108

  Fly   398 DGAGSAVRRNLTMPVL-------------NITAQMGNHAYMPCQIHRLSDKPVSWVRMRDNHIIS 449
            |.....:|.:..:..:             |:|..:...|.:.|.:..|....::|:|:....|::
  Fly   109 DELLEDIREDTVVNAIPEKDLPKFGELLQNVTVPVSREAVLQCVVDNLQTYKIAWLRVDTQTILT 173

  Fly   450 VDETTFIADERFQSIYQEDHDYTWSLQIKYVEPSDAGWYECQMATEPKLSAKVHLQIVKP----- 509
            :.......:.|....:.|..  .|.|:|:.|:.||.|||.||:.|:|..|...:|.:|.|
  Fly   174 IQNHVITKNHRMSITHAEKR--AWILRIRDVKESDKGWYMCQINTDPMKSQVGYLDVVVPPDILD 236

  Fly   510 ---KTELIGDQSRFVKAGSKVALHCIVRGTLDPPKYIIWFR----------GQKKISDSDERTGW 561
               .|:::      ::.||.|.|.|...|:  |...|.|.|          |.:.::.:
  Fly   237 YPTSTDMV------IREGSNVTLKCAATGS--PTPTITWRREGGELIPLPNGAEAVAYN------ 287

  Fly   562 YTQLDRNIFGTVGDNQNTIGS-LIIPLVRKEDSGNYTCQPSNSVSVSVDLHVL 613
                               || |.|..|.:.:.|.|.|..||.:..:|...|:
  Fly   288 -------------------GSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVM 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	19/76 (25%)
		Ig	415..507	CDD:299845	24/91 (26%)
		IG_like	521..612	CDD:214653	22/101 (22%)
		IGc2	524..605	CDD:197706	21/91 (23%)
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	25/94 (27%)
		IG_like	137..230	CDD:214653	25/94 (27%)
		IG_like	240..324	CDD:214653	24/115 (21%)
		IGc2	247..310	CDD:197706	19/89 (21%)
		Ig	327..419	CDD:299845
		IG_like	343..420	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I12107
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810