DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr17 and Negr1

DIOPT Version :9

Sequence 1:NP_001287297.1 Gene:dpr17 / 41470 FlyBaseID:FBgn0051361 Length:664 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:316 Identity:63/316 - (19%)
Similarity:109/316 - (34%) Gaps:113/316 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   414 NITAQMGNHAYMPCQIHRLSDKPVSWVRMRDNHIISVDETTFIADERFQSIYQEDHDYTWSLQIK 478
            |:..:.|:.|.:.|.:...:.|. :|  :..:.||......:..|.|.........||  ||||:
Mouse    41 NMLVRKGDTAVLRCYLEDGASKG-AW--LNRSSIIFAGGDKWSVDPRVSISTLNKRDY--SLQIQ 100

  Fly   479 YVEPSDAGWYECQMATE--PKLSAKVHLQI-VKPKT-ELIGDQSRFVKAGSKVALHCIVRG---- 535
            .|:.:|.|.|.|.:.|:  |: :.:|||.: |.||. ::..|.:  :..|:.|.|.|:..|    
Mouse   101 NVDVTDDGPYTCSVQTQHTPR-TMQVHLTVQVPPKIYDISNDMT--INEGTNVTLTCLATGKPEP 162

  Fly   536 -------------------------TLD------------------------------------- 538
                                     |.|                                     
Mouse   163 VISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVIVNFAPTIQEIKSG 227

  Fly   539 -----------------PPKYIIWFRGQKKISDSDERTGWYTQLDRNIFGTVGDNQNTIGSLIIP 586
                             ||....|::|:|::.:..:             |.:..|.:|...|.:.
Mouse   228 TVTPGRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQ-------------GIIIQNFSTRSILTVT 279

  Fly   587 LVRKEDSGNYTCQPSN---SVSVSVDLHVLSGEYSASAIMSTAARTTKGG--RSTC 637
            .|.:|..|||||..:|   :.:.|:.|:.:....::|.:.|.|..|.:.|  .|.|
Mouse   280 NVTQEHFGNYTCVAANKLGTTNASLPLNQIIEPTTSSPVTSPAPSTAQYGITGSAC 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr17NP_001287297.1 IG_like 414..491 CDD:214653 20/76 (26%)
Ig 415..507 CDD:299845 25/94 (27%)
IG_like 521..612 CDD:214653 26/176 (15%)
IGc2 524..605 CDD:197706 24/166 (14%)
Negr1XP_036019026.1 FR1 38..55 CDD:409353 3/13 (23%)
Ig strand A' 40..46 CDD:409353 1/4 (25%)
IG_like 41..129 CDD:214653 26/93 (28%)
Ig strand B 48..56 CDD:409353 2/7 (29%)
CDR1 56..60 CDD:409353 0/3 (0%)
FR2 61..68 CDD:409353 2/9 (22%)
Ig strand C 61..67 CDD:409353 2/8 (25%)
CDR2 69..79 CDD:409353 2/9 (22%)
Ig strand C' 71..74 CDD:409353 2/2 (100%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 13/36 (36%)
Ig strand D 84..91 CDD:409353 1/6 (17%)
Ig strand E 94..100 CDD:409353 5/7 (71%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 4/9 (44%)
FR4 122..129 CDD:409353 3/6 (50%)
Ig strand A' 139..144 CDD:409353 1/6 (17%)
IGc2 146..204 CDD:197706 7/57 (12%)
Ig strand B 150..157 CDD:409353 3/6 (50%)
Ig strand C 163..168 CDD:409353 0/4 (0%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 0/5 (0%)
Ig strand F 193..200 CDD:409353 0/6 (0%)
Ig_3 219..295 CDD:404760 16/88 (18%)
putative Ig strand A 219..225 CDD:409353 0/5 (0%)
Ig strand B 235..239 CDD:409353 0/3 (0%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 45 1.000 Domainoid score I12107
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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