DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr17 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_001363879.1	Gene:	Igsf9b / 315510	RGDID:	1564717	Length:	1441	Species:	Rattus norvegicus

Alignment Length:	317	Identity:	70/317 - (22%)
Similarity:	107/317 - (33%)	Gaps:	136/317 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   415 ITAQMGNHAYMPCQ-IHRLSDKP----VSWVRMRDNHIISVDETTFIADERFQSIYQEDH---DY 471
            :||:.|....:.|. ||.::.:|    |.|.:      ..|....||   :|.  |...|   :|
  Rat    33 VTARAGEGVVLRCDVIHPVTGQPPPYVVEWFK------FGVPIPIFI---KFG--YYPPHVDPEY 86

  Fly   472 TW--------SLQIKYVEPSDAGWYECQMATEPKL------SAKVHLQIVKPKTELIGDQSRFVK 522
            ..        ||:::.|...|.|||||::....:.      .:.|||.|..|.| ......::::
  Rat    87 AGRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPT-FTETPPQYIE 150

  Fly   523 A--GSKVALHCIVRGTLDPPKYIIWFR--------GQKKISD--------SDERTG--------- 560
            |  |..:.:.|...|  :|...:.|.:        |:.::||        |.|..|
  Rat   151 AKEGGSITMTCTAFG--NPKPIVTWLKEGTLLSASGKYQVSDGSLTVTSVSREDRGAYTCRAYSI 213

  Fly   561 -------------------------------------------------WYTQLDRNIFGTVGDN 576
                                                             ||.| |.|::     .
  Rat   214 QGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQ-DENVY-----F 272

  Fly   577 QNTI---------GSLIIPLVRKEDSGNYTCQPSNSVSVSVDLHVLSGEYSASAIMS 624
            ||.:         |:|||..|:.||:|.|||.||||:..|.         ||||.::
  Rat   273 QNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSP---------SASAYLT 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	24/91 (26%)
		Ig	415..507	CDD:299845	28/113 (25%)
		IG_like	521..612	CDD:214653	35/175 (20%)
		IGc2	524..605	CDD:197706	33/163 (20%)
Igsf9b	NP_001363879.1	PHA03247	<898..1246	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1044
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1111..1332
		Ig	41..115	CDD:319273	22/84 (26%)
		I-set	139..225	CDD:369462	13/88 (15%)
		Ig	229..321	CDD:386229	27/107 (25%)
		Ig	<353..414	CDD:386229
		Ig	438..502	CDD:319273
		FN3	510..605	CDD:238020
		FN3	621..703	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	762..821
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900