DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr17 and kirre

DIOPT Version :9

Sequence 1:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster

Alignment Length:	298	Identity:	59/298 - (19%)
Similarity:	120/298 - (40%)	Gaps:	56/298 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 AAEAAAQAAAAKTSSEAVTMSPEEQRRQMFNEQHSYLAAHRDGGDGAGSAVRRNLTMPVLNITAQ 418
            ::.:::.::::.:||.|.:.:.:|.:.:              |||..|    ::..|...:.||.
  Fly    48 SSSSSSSSSSSGSSSAAASSANDESKPK--------------GGDNGG----QHFAMEPQDQTAV 94

  Fly   419 MGNHAYMPCQIHRLSDK--PVSWVRMRDNHIISVDETTFIADERFQSIYQEDHDYTWSLQIKYVE 481
            :|:...:||   |:.:|  .:.|.  :|:..:. ........||: |:...|.:..:||.|..:.
  Fly    95 VGSRVTLPC---RVMEKVGALQWT--KDDFGLG-QHRNLSGFERY-SMVGSDEEGDFSLDIYPLM 152

  Fly   482 PSDAGWYECQMATEPKLSAKVHLQIVKPKTELIGDQSRFVKAGS--------KVALHCIVRGTLD 538
            ..|...|:||:...|:....:..:..| .|.|:..::..:..|.        ::.|.|:.:|. .
  Fly   153 LDDDAKYQCQVGPGPQGEQGIRSRFAK-LTVLVPPEAPKITQGDYLVTTEDREIELECVSQGG-K 215

  Fly   539 PPKYIIWFRGQKKISDSDERTGWYTQLDRNIFGTVGDNQNTIGSLIIPLVRKEDSGN--YTCQPS 601
            |...|.|..|...:         .|:....:...:.|::......|:.|..|::..|  :|||..
  Fly   216 PAAEITWIDGLGNV---------LTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQ 271

  Fly   602 NSV-----SVSVDLHVLSGEYSASAIMSTAARTTKGGR 634
            |:.     |..:.|.|   :|:...|:|.......||:
  Fly   272 NTADRTYRSAKLLLEV---KYAPKVIVSVVGGALAGGK 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	18/78 (23%)
		Ig	415..507	CDD:299845	21/93 (23%)
		IG_like	521..612	CDD:214653	20/105 (19%)
		IGc2	524..605	CDD:197706	18/95 (19%)
kirre	NP_001245505.1	Ig	87..183	CDD:299845	23/103 (22%)
		IG_like	88..182	CDD:214653	22/101 (22%)
		C2-set_2	189..279	CDD:285423	18/99 (18%)
		Ig_2	307..379	CDD:290606	59/298 (20%)
		I-set	382..462	CDD:254352
		IGc2	396..446	CDD:197706
		Ig	466..561	CDD:299845
		IG_like	478..561	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810