DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr17 and Igsf9

DIOPT Version :9

Sequence 1:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_001100667.1	Gene:	Igsf9 / 304982	RGDID:	1304566	Length:	1179	Species:	Rattus norvegicus

Alignment Length:	334	Identity:	75/334 - (22%)
Similarity:	111/334 - (33%)	Gaps:	146/334 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   396 GGDGAGSAVRRNLTMPVLNITAQMGNHAYMPCQIHRLSDKP----VSWVRMRDNHIISVDETTFI 456
            |.||     ||.  ..|:::..:.|..|.:.|.:...:.:|    :.|:|.  ..::.:    ||
  Rat    17 GADG-----RRK--PEVVSVVGRAGESAVLGCDLLPPAGRPPLHVIEWLRF--GFLLPI----FI 68

  Fly   457 ADERFQSIYQE--DHDYTW--------SLQIKYVEPSDAGWYECQMATEPKLSAK--------VH 503
               :| .:|..  |.||..        ||||:.:...|.|||||::....:.|.:        ||
  Rat    69 ---QF-GLYSPRIDPDYVGRVRLQTGASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVH 129

  Fly   504 LQIVKPKTELIGDQSRF---------VKAGSKVALHCIVRGTLDPPKYIIW-FRGQ---KKISDS 555
            |.:..|        .:|         ||....|.|.|:..|:  |..|:.| ||||   |.....
  Rat   130 LTVNSP--------PQFQETPPLVLEVKELEAVTLRCVALGS--PQPYVTWKFRGQDLGKGQGQV 184

  Fly   556 DERTG--WYTQLDRNIFGTVGD------------------------------NQNTI-------- 580
            ..|.|  |..:::|   |:.||                              |.||:
  Rat   185 QVRNGTLWIRRVER---GSAGDYTCQASSTEGSVTHTTQLLVLGPPVIVVPPNNNTVNASQDVSL 246

  Fly   581 -------------------------------------GSLIIPLVRKEDSGNYTCQPSNSV---- 604
                                                 |||.:...:.:|:|:|||.|||..
  Rat   247 ACRAEAYPANLTYSWFQDRINVFHISRLQSRVRILVDGSLWLQATQPDDAGHYTCVPSNGFPHPP 311

  Fly   605 SVSVDLHVL 613
            |.|..|.||
  Rat   312 SASAYLTVL 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	22/90 (24%)
		Ig	415..507	CDD:299845	27/113 (24%)
		IG_like	521..612	CDD:214653	38/175 (22%)
		IGc2	524..605	CDD:197706	33/165 (20%)
Igsf9	NP_001100667.1	IG	28..110	CDD:214652	23/91 (25%)
		Ig strand A	136..139	CDD:409353	0/2 (0%)
		IG_like	143..223	CDD:214653	21/84 (25%)
		Ig strand A'	145..148	CDD:409353	0/2 (0%)
		Ig strand B	154..161	CDD:409353	3/6 (50%)
		Ig strand C	167..172	CDD:409353	2/4 (50%)
		Ig strand C'	175..177	CDD:409353	1/1 (100%)
		Ig strand D	183..187	CDD:409353	0/3 (0%)
		Ig strand E	189..193	CDD:409353	1/3 (33%)
		Ig strand F	202..210	CDD:409353	2/7 (29%)
		Ig strand G	213..223	CDD:409353	0/9 (0%)
		Ig_3	226..305	CDD:404760	12/78 (15%)
		putative Ig strand A	226..230	CDD:409353	0/3 (0%)
		putative Ig strand A'	235..239	CDD:409353	2/3 (67%)
		putative Ig strand B	241..251	CDD:409353	0/9 (0%)
		putative Ig strand C'	267..270	CDD:409353	0/2 (0%)
		putative Ig strand D	279..282	CDD:409353	0/2 (0%)
		putative Ig strand E	284..290	CDD:409353	3/5 (60%)
		putative Ig strand F	297..305	CDD:409353	5/7 (71%)
		putative Ig strand G	310..319	CDD:409353	3/8 (38%)
		Ig	322..407	CDD:416386
		Ig strand A'	324..328	CDD:409353
		Ig strand B	333..347	CDD:409353
		Ig strand C	353..359	CDD:409353
		Ig strand C'	362..364	CDD:409353
		Ig strand D	371..374	CDD:409353
		Ig strand E	378..382	CDD:409353
		Ig strand F	391..399	CDD:409353
		Ig	418..503	CDD:416386
		Ig strand A	418..421	CDD:409353
		Ig strand A'	427..430	CDD:409353
		Ig strand B	436..443	CDD:409353
		Ig strand C	449..454	CDD:409353
		Ig strand C'	457..459	CDD:409353
		Ig strand D	462..466	CDD:409353
		Ig strand E	469..473	CDD:409353
		Ig strand F	482..490	CDD:409353
		Ig strand G	493..503	CDD:409353
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	766..807
		PHA03247	<777..1062	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..846
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	869..895
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..979
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding. /evidence=ECO:0000250	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900