DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr17 and ncam1a

DIOPT Version :9

Sequence 1:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	XP_009293555.1	Gene:	ncam1a / 30447	ZFINID:	ZDB-GENE-990415-31	Length:	1010	Species:	Danio rerio

Alignment Length:	252	Identity:	63/252 - (25%)
Similarity:	104/252 - (41%)	Gaps:	32/252 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   413 LNITAQMGNHAYMPCQIHRLSDKPVSWVRMRDNHIISVDETTFIADERFQSIYQEDHDYTWSLQI 477
            ||.||.:.....:.|......:..|.|.|         ..|...:||:: |:.::..:.|    |
Zfish   218 LNATADINQAVTLACHADGYPEPTVKWAR---------GNTELESDEKY-SLNEDGSELT----I 268

  Fly   478 KYVEPSDAGWYECQMATEP-KLSAKVHLQI-VKPKTELIGDQSRFVKAGSKVALHCIVRGTLDPP 540
            |.|...|.|.|:|....:. :.|.:|.|.: |:||...:.:|:. .:...::.|.|...|  ||.
Zfish   269 KDVNKLDEGDYKCIARNKAGERSEEVTLNVFVQPKITFLENQTA-SELEEQITLTCEATG--DPT 330

  Fly   541 KYIIWFRGQKKISDSDERTGW-----YTQLDRNIFGTVGDNQNTIGSLIIPLVRKEDSGNYTCQP 600
            ..|||..| :::...:|:..|     :..||.|:   |..:...:.||.:..|:..|:|.|.|..
Zfish   331 PNIIWSFG-RRVFTENEQASWTRPEKHKSLDGNV---VVRSDARVSSLTLKYVQFTDAGQYLCTA 391

  Fly   601 SNSVSVSVDLHVLSGEYSASAIMSTAARTTKGGRS--TCHSTLGLLGILGLLWAMQG 655
            .||:...:....|...|:.......|..|.:|..:  ||.: |...| ..:||...|
Zfish   392 RNSIGQDIQSMYLEVRYAPKIQGPQAVFTWEGNPANITCEA-LAHPG-ASVLWFRDG 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	18/76 (24%)
		Ig	415..507	CDD:299845	21/93 (23%)
		IG_like	521..612	CDD:214653	24/95 (25%)
		IGc2	524..605	CDD:197706	24/85 (28%)
ncam1a	XP_009293555.1	Ig	20..112	CDD:299845
		I-set	21..111	CDD:254352
		IG_like	121..200	CDD:214653
		IGc2	128..189	CDD:197706
		Ig	208..301	CDD:299845	23/96 (24%)
		IG_like	219..298	CDD:214653	22/92 (24%)
		Ig	300..406	CDD:299845	29/112 (26%)
		IG_like	308..406	CDD:214653	26/104 (25%)
		ig	413..498	CDD:278476	10/36 (28%)
		IG_like	415..498	CDD:214653	10/34 (29%)
		fn3	505..589	CDD:278470
		FN3	624..715	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900