DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr17 and ntm

DIOPT Version :9

Sequence 1:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	366	Identity:	78/366 - (21%)
Similarity:	118/366 - (32%)	Gaps:	153/366 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   414 NITAQMGNHAYMPCQIHRLSDKPVSW-----VRMRDNHIISVD-ETTFIADERFQSIYQEDHDYT 472
            |:|.:.|:.|.:.|.:.....: |:|     :....|...|:| ....:|:.:.|
Frog    45 NVTVRQGDSAILRCTVDNRVTR-VAWLNRSTILYTGNDKWSIDPRVVLLANTKSQ---------- 98

  Fly   473 WSLQIKYVEPSDAGWYECQMATE--PKLSAKVHLQIVKPKTELIGDQSRFVKAGSKVALHCIVRG 535
            :|::|:.|:..|.|.|.|.:.|:  ||.| :|||.:..|...:....|..|..||.|:|.||..|
Frog    99 YSIEIQNVDIYDEGPYTCSVQTDNHPKTS-RVHLIVQVPPRIVDISSSIAVNEGSNVSLICIANG 162

  Fly   536 TLDP--------------------------------------------------------PKYII 544
            ..:|                                                        |.||:
Frog   163 RPEPVVNWRYLSPKARGFVSEDEYLEITGITREQSGIYECSASNDVSAPDVRRVKLTVNYPPYIL 227

  Fly   545 ----------------------------WFRGQKKISDSDERTGWYTQLDRNIFGTVGDNQNTIG 581
                                        |::..|::|||     |.        |...:|:.||.
Frog   228 DAQNIGAPLGHRGILQCEASAVPAADFFWYKEDKRLSDS-----WR--------GVKVENRETIS 279

  Fly   582 SLIIPLVRKEDSGNYTCQPSNSVSVSVDLHVLSGEYSASAIM---------------STAARTTK 631
            .:....|.::|.|||||...|          |.|..:||.|:               ||||.|..
Frog   280 RVTFLNVSEQDYGNYTCMAKN----------LLGHSNASIILFELFQSTSSPLLQEESTAALTPL 334

  Fly   632 GGRSTCHSTLGLLG---------ILGLLWAMQGAMHTPPTQ 663
            .|....|.  |..|         :|.||..:..::..||.|
Frog   335 KGPGAVHD--GNSGSTQCSFCAPLLILLLLLPFSLLLPPAQ 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	18/82 (22%)
		Ig	415..507	CDD:299845	25/99 (25%)
		IG_like	521..612	CDD:214653	30/174 (17%)
		IGc2	524..605	CDD:197706	29/164 (18%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	26/99 (26%)
		IG_like	45..133	CDD:214653	26/99 (26%)
		IG_like	143..220	CDD:214653	10/76 (13%)
		IGc2	150..209	CDD:197706	8/58 (14%)
		ig	227..311	CDD:278476	22/106 (21%)
		IG_like	230..311	CDD:214653	22/103 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000