DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr17 and Kirrel2

DIOPT Version :9

Sequence 1:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	XP_038957463.1	Gene:	Kirrel2 / 100359836	RGDID:	1308456	Length:	711	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	63/266 - (23%)
Similarity:	100/266 - (37%)	Gaps:	64/266 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   419 MGNHAYMPCQIHRLSDKPVSWVR-------MRD-----NHIISVDETTFIADERFQSIYQEDHDY 471
            :|..|.:||.:...... |.|.:       .||     .:.||.:..:            ..||
  Rat    45 LGQEARLPCALGAYRGL-VQWTKDGLALGGERDLPGWSRYWISGNSAS------------GQHD- 95

  Fly   472 TWSLQIKYVEPSDAGWYECQMATEPKL---SAKVHLQIVKPKTELIGDQSRFVKAGSKVALHCIV 533
               |.||.||..|...|||| |::..|   .|::|:.:.....:::|..|..:.||....|.|..
  Rat    96 ---LHIKPVELEDEASYECQ-ASQAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRS 156

  Fly   534 RGTLDPPKYIIWFRGQKKISDS--------DERTGWYTQLDRNIFGTVGDNQNTIGSLIIPLVRK 590
            ||...|...::|||...::..:        |:.|           |||   :||   |.:....:
  Rat   157 RGDARPAPELLWFRDGIRLDGTSFHQITLRDKAT-----------GTV---ENT---LFLTPSSQ 204

  Fly   591 EDSGNYTCQP-SNSVSVSVDLHV-LSGEYSASAIMSTAARTTKGGRST---CHSTLGLLGILGLL 650
            :|.....|:. |.::....|..| ||.:|.....:|...:|.:.|...   |.:| ....:.|..
  Rat   205 DDGATLICRARSQALPTGRDTAVTLSLQYPPMVTLSAEPQTAQEGEKVTFLCQAT-AQPPVTGYR 268

  Fly   651 WAMQGA 656
            ||..|:
  Rat   269 WAKGGS 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	20/83 (24%)
		Ig	415..507	CDD:299845	26/102 (25%)
		IG_like	521..612	CDD:214653	22/99 (22%)
		IGc2	524..605	CDD:197706	20/89 (22%)
Kirrel2	XP_038957463.1	IG_like	38..127	CDD:214653	25/99 (25%)
		Ig strand A'	40..44	CDD:409353
		Ig strand B	48..57	CDD:409353	3/8 (38%)
		Ig strand C	62..66	CDD:409353	2/3 (67%)
		Ig strand D	75..85	CDD:409353	2/9 (22%)
		Ig strand E	88..100	CDD:409353	4/27 (15%)
		Ig strand F	107..115	CDD:409353	5/8 (63%)
		Ig strand G	117..127	CDD:409353	2/9 (22%)
		Ig	133..231	CDD:416386	26/114 (23%)
		Ig strand A	134..137	CDD:409353	0/2 (0%)
		Ig strand A'	140..144	CDD:409353	1/3 (33%)
		Ig strand B	151..158	CDD:409353	2/6 (33%)
		Ig strand C	164..169	CDD:409353	0/4 (0%)
		Ig strand C'	172..174	CDD:409353	0/1 (0%)
		Ig strand D	177..184	CDD:409353	0/6 (0%)
		Ig strand E	191..199	CDD:409353	6/13 (46%)
		Ig strand F	208..216	CDD:409353	1/7 (14%)
		Ig strand G	222..228	CDD:409353	1/5 (20%)
		Ig_3	234..303	CDD:404760	9/42 (21%)
		Ig strand B	252..256	CDD:409353	0/3 (0%)
		Ig strand C	266..270	CDD:409353	1/3 (33%)
		Ig strand E	283..286	CDD:409353
		Ig strand F	292..301	CDD:409353
		Ig strand G	309..312	CDD:409353
		Ig	326..403	CDD:416386
		Ig strand A'	327..332	CDD:409353
		Ig strand B	335..344	CDD:409353
		Ig strand C	350..354	CDD:409353
		Ig strand C'	357..359	CDD:409353
		Ig strand D	362..365	CDD:409353
		Ig strand E	366..371	CDD:409353
		Ig strand F	379..387	CDD:409353
		Ig strand G	393..403	CDD:409353
		Ig	405..509	CDD:416386
		Ig strand A	406..410	CDD:409353
		Ig strand A'	412..415	CDD:409353
		Ig strand B	423..430	CDD:409353
		Ig strand C	437..442	CDD:409353
		Ig strand C'	444..447	CDD:409353
		Ig strand D	455..462	CDD:409353
		Ig strand E	472..479	CDD:409353
		Ig strand F	490..497	CDD:409353
		Ig strand G	500..507	CDD:409353
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900